3 25 2024

Hi, This Week in Medicine, we will be discussing

New England Journal of Medicine

Risk of Autism after Prenatal Topiramate, Valproate, or Lamotrigine Exposure

Ribociclib plus Endocrine Therapy in Early Breast Cancer

Intrathecal Gene Therapy for Giant Axonal Neuropathy

Anti–Interleukin-23 Autoantibodies in Adult-Onset Immunodeficiency

  Journal of  American Medical Association

Vibration-Controlled Transient Elastography Scores to Predict Liver-Related Events in Steatotic Liver Disease

Skin Biopsy Detection of Phosphorylated α-Synuclein in Patients With Synucleinopathies

Annals of Internal Medicine

Association of Low Glomerular Filtration Rate With Adverse Outcomes at Older Age in a Large Population With Routinely Measured Cystatin C

Surgery, Needle Fasciotomy, or Collagenase Injection for Dupuytren Contracture: A Randomized Controlled Trial

  British Medical Journal

Current safeguards, risk mitigation, and transparency measures of large language models against the generation of health disinformation: repeated cross sectional analysis

  Lancet

Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults

 Journal of Clinical Oncology

Neoadjuvant Chemotherapy in High-Grade Myxoid Liposarcoma: Results of the Expanded Cohort of a Randomized Trial From Italian (ISG), Spanish (GEIS), French (FSG), and Polish Sarcoma Groups (PSG)

  journal of Hepatology

Global survey of stigma among physicians and patients with nonalcoholic fatty liver disease

 Clinical Gastroenterology

Buprenorphine Versus Diclofenac for Pain Relief in Acute Pancreatitis: A Double-Blinded Randomized Controlled Trial

Sex Differences in Treatment Response to Nucleos(t)ide Therapy in Chronic Hepatitis B: A Multicenter Longitudinal Study

 Clinical Infectious Diseases

Emulating a Target Trial of Shorter Compared to Longer Course of Antibiotic Therapy for Gram-Negative Bacteremia

  Journal of Clinical Rheumatology 

Persistent Risk of Developing Autoimmune Diseases Associated With COVID-19: An Observational Study Using an Electronic Medical Record Database in Japan

Arthritis and Rheumatology

Three-Dimensional Chromosomal Landscape Revealing miR-146a Dysfunctional Enhancer in Lupus and Establishing a CRISPR-Mediated Approach to Inhibit the Interferon Pathway

Circulation

Arterial Thromboembolism in Patients With Atrial Fibrillation and CHA2DS2-VASc Score 1: A Nationwide Study

American College of Cardiology

TAVR or SAVR in Severe Aortic Stenosis and Small Aortic Annulus

 Journals of the American College of Cardiology

Angiotensin Receptor-Neprilysin Inhibition in Patients With STEMI vs NSTEMI

  Journal of Clinical Endocrinology & Metabolism

High Incidence of Diabetes Mellitus After Distal Pancreatectomy and Its Predictors: A Long-term Follow-up Study 

  Neurology:

Effect of Evobrutinib on Slowly Expanding Lesion Volume in Relapsing Multiple Sclerosis: A Post Hoc Analysis of a Phase 2 Trial

  Chest

Preserved Ratio Impaired Spirometry and COPD Accelerate Frailty Progression

Changes in Respiratory Mechanics With Trunk Inclination Differs Between Patients With ARDS With and Without Obesity

Prospective Evaluation of Venous Excess Ultrasound for Estimation of Venous Congestion

 The American Journal of Respiratory and Critical Care Medicine

Extracorporeal Carbon Dioxide Removal to Avoid Invasive Ventilation During Exacerbations of Chronic Obstructive Pulmonary Disease: VENT-AVOID Trial – A Randomized Clinical Trial

 Clinical Journal of American Society of Nephrology

Association of Bioimpedance Parameters with Increases in Blood Pressure during Hemodialysis

Drug-Coated Balloon Angioplasty for Dysfunctional Arteriovenous Hemodialysis Fistulae: A Randomized Controlled Trial

  Kidney International reports

Ecological Momentary Assessment to Explore Fatigue, Mood, and Physical Activity Levels in People Receiving Peritoneal Dialysis