30 Day FDA Drug Development in Cannabinoid and Psychedelic Spaces - Day 26 Advanced Topics in Process Chemistry and Scalability

This podcast episode explores the complex challenges of scaling up production of cannabinoid and psychedelic APIs (Active Pharmaceutical Ingredients) from laboratory to commercial scale. Using Watson's Pharmaceutical Process Development as a guide, the discussion covers key aspects including:- Balancing yield maximization, cost minimization, and waste management while maintaining product safety and efficacy- The differences between batch and continuous processing methods- Specific challenges with sensitive compounds from natural sources, including quality control and contamination prevention- Environmental considerations and sustainable production methods, including green chemistry approachesThe episode provides detailed insights into both traditional extraction methods and emerging synthetic approaches for producing these therapeutic compounds.