33: What Actually Moves Your Cholesterol (And Why It's Probably Not Saturated Fat) Part 2 episode artwork

EPISODE · Jun 10, 2026 · 20 MIN

33: What Actually Moves Your Cholesterol (And Why It's Probably Not Saturated Fat) Part 2

from Mornings with Megan · host Megan Pfiffner

Last week I told you that the 6% saturated fat guideline is not what it appears to be. This week we get into the part that actually matters: what does the research say really moves your cholesterol numbers?This episode lives in the Fuel pillar of the Perimenopause Matrix. Fuel is about how your body uses energy, and for a lot of women in perimenopause, the lipid picture is one of the first places the Fuel pillar starts to signal.I put every major lever side by side with real numbers: saturated fat restriction, psyllium fiber, oat beta-glucan, and statins. I walk through the two key trials in detail, including one where the same dietary change caused a 54-point LDL drop in some people and a 30-point rise in others. I explain why LDL-C and ApoB do not always tell the same story, and why that gap matters for 20 to 30% of women. And I share my own experiment, including the part where doing everything right made my LDL go up by over 30 points.What you will learn:The LDL-C versus ApoB distinction and why it changes how you read your lipid panelHow the RISSCI-1 and GET-READI trials actually performed, including the findings that rarely get mentionedHow fiber, exercise, and saturated fat restriction compare head to headWhat the Fuel pillar framework tells us about lipid management in perimenopauseHow to run a clean personal experiment to find out how your body actually respondsThis is Part 2 of a two-part series. Listen to Episode 32 first.👉 ⁠Full Episode Show Notes⁠About the Perimenopause Matrix:The Matrix is my framework for navigating perimenopause across 6 pillars: Fuel, Move, Recharge, Regulate, Connect, and Clean. But this episode isn't about optimizing all 6 - it's about choosing the ONE that matters most in YOUR current reality.🧬 Ready to stop guessing?I help women interpret their labs so they can make nutrition decisions based on data, not diet trends.👉 Book your personalized Lab Review here🎁 FREE RESOURCE: Download the free Perimenopause Decoder . It helps you understand what's happening during perimenopause so you can make decisions from a place of clarity, not chaos.📱 CONNECT WITH ME:Website⁠⁠Instagram⁠⁠LinkedIn⁠Facebook ⁠YoutubeYou're not crazy. You're not broken. You're not alone. And you absolutely deserve to feel like yourself again.Listen to Mornings with Megan Podcast 🎧 New episodes drop every Wednesday!AppleSpotifyAmazonYoutube

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33: What Actually Moves Your Cholesterol (And Why It's Probably Not Saturated Fat) Part 2

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