333: When Mutualists Murder

from This Week in Microbiology · host Vincent Racaniello, Michael Schmidt, Michele Swanson,Petra Levin

TWiM explains how a mutualistic model bacterium can become lethal in a non-symbiotic host, and engineering a kill switch into a tuberculosis vaccine for improved safety. Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson. Subscribe to TWiM (free) on Apple Podcasts, Spotify, Android, RSS, or by email. Become a patron of TWiM. Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Links for this episode When a mutualist becomes lethal (mBio) A lasting symbiosis (Nat Rev Micro) A kill switch for BCG (Nat Micro) Engineering mycobacteria for vaccination (Nat Micro) Take the TWiM Listener survey! Send your microbiology questions and comments (email or recorded audio) to [email protected]

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This episode is 58 minutes long.

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This episode was published on June 7, 2025.

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