334.How Your Microbiome Controls Your Health with Leo Grady, Founder and CEO of Jona episode artwork

EPISODE · Nov 14, 2025 · 52 MIN

334.How Your Microbiome Controls Your Health with Leo Grady, Founder and CEO of Jona

from State of Medtech · host State of Medtech

Could your gut be the key to solving chronic fatigue, autoimmune issues, or even mental health? Leo Grady, Founder and CEO of Jona, joins the show to explain how AI is unlocking the secrets of the microbiome one stool sample at a time.From fecal transplants to personalized diet plans, learn how deep sequencing and transparent science are changing healthcare without the guesswork. Stream the episode and take control of your health from the inside out.Episode Breakdown0:00 – Why the gut microbiome is the missing key to modern medicine  1:00 – Meet Leo Grady, Founder and CEO of Jona: from AI in radiology to founding Jona Health  2:30 – The moment AI met biology: how data revealed the gut’s hidden power  4:00 – Why chronic disease, obesity, and inflammation start in the microbiome  6:00 – Building an AI model for the human gut: challenges and breakthroughs  8:30 – From Siemens Healthineers to Jona: Leo’s leap into microbiome medicine  10:00 – The science behind poop transplants and what they teach us  12:00 – How diet, stress, and sleep rewrite your gut ecosystem  14:30 – Using sequencing data and AI to personalize nutrition  35:00 – The new wave of evidence-based biohacking  37:00 – AI vs. traditional medicine: merging two worlds of care  39:00 – Surprising discoveries from Jona’s real-world patient data  41:00 – How antibiotics, fasting, and fiber affect the microbiome  43:00 – The gut as your body’s sensory organ: interpreting internal signals  45:00 – Top foods that rebuild the microbiome naturally  47:00 – How wearables and gut data together unlock holistic health  49:00 – Leo’s daily health stack: protein, recovery, and AI tracking  51:00 – Final insights: why the microbiome revolution is just beginning  52:00 – Outro: subscribe, share, and take control of your gut healthAre you a medtech CEO in need of some marketing help attracting investors, growing sales pipeline, and more? Go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠GrowMyMedtech.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to book time for a free analysis.Subscribe to our Youtube Channel⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/channel/UCGpL_rGt1LQJwinMq_K7gfg⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to our LinkedIn Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.stateofmedtechpodcast.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow The State of MedTech onLinkedIn ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/company/thestateofmedtech⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/stateofmedtech/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TikTok ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.tiktok.com/@stateofmedtech⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠X ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twitter.com/StateofMedTech⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/stateofmedtech/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow Omar M. Khateeb onLinkedIn ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/okhateeb/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/omar.m.khateeb/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TikTok ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.tiktok.com/@omarkhateebofficial⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠X ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twitter.com/OmarMKhateeb⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/OmarMKhateeb/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠This podcast is for informational and educational purposes only and does not constitute financial, investment, legal, or medical advice. The views and opinions expressed by hosts and guests are their own and do not necessarily reflect those of State of MedTech LLC. Nothing discussed on this podcast should be interpreted as a recommendation to buy, sell, or hold any investment or security. Listeners should conduct their own due diligence and consult with a qualified financial advisor, attorney, or other professional before making any financial or investment decisions#GutHealth #Microbiome #Biohacking #MedTech #HealthTech

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334.How Your Microbiome Controls Your Health with Leo Grady, Founder and CEO of Jona

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