EPISODE · Jan 1, 2026 · 16 MIN
352-人胶质瘤多组学图谱及其治疗与复发
from 聊聊Sci
这项研究通过构建BRUCE队列，对310名胶质瘤患者的677份样本进行了深入分析。研究者整合了空间蛋白质组学、转录组学和糖组学，揭示了从诊断到复发过程中肿瘤微环境的复杂演变。调查结果显示，由于肿瘤抗原（如B7H3和EGFR）在细胞间存在显著的表达差异，现有的单一靶向疗法面临巨大挑战。此外，研究发现N-糖基化修饰是区分肿瘤分级的关键指标，而免疫分子特征则是预测胶质母细胞瘤患者生存率的最强因素。该研究不仅识别了与复发相关的特定免疫空间生态位，还为未来的精准治疗和临床干预提供了开放获取的多组学资源库。References: Piyadasa H, Oberlton B, Ribi M, et al. Multi-omic landscape of human gliomas from diagnosis to treatment and recurrence[J]. Cancer Cell, 2025.前往小宇宙评论区与主播互动
Embed this episode
Ready to play
352-人胶质瘤多组学图谱及其治疗与复发
0:00
16:52
1×
No transcript for this episode yet
Similar Episodes
No similar episodes found.
Similar Podcasts
Forfeiture Book Review: Ecocide and Sci-Fi
JP et al.
A whizz bang review of the complex themes in the new ecological Sci-Fi novel, FORFEITURE by JP Nebra
Deep Dream State
Neural Nets And Pretty Patterns
Deep Dream State is a full-cast dystopian sci-fi and desire horror audio drama by Neural Nets and Pretty Patterns. As the originating work of desire horror, it locates the uncanny inside wanting itself. While conventional horror positions you against a threat, desire horror implicates you in it. The horror emerges from recognition: the realization of why characters stay, and why surrender feels like relief. Since 2017, the show has used research in dream science, surveillance studies, behavioral economics, and advertising technology to examine systems of control through immersive sound design and full-cast performance.
Frequently Asked Questions
How long is this episode of 聊聊Sci?
This episode is 16 minutes long.
When was this 聊聊Sci episode published?
This episode was published on January 1, 2026.
Can I download this 聊聊Sci episode?
Yes. Use the download control on the episode player to save the publisher-provided media file.
URL copied to clipboard!