#37 – Do Psychedelics Leave Biological Fingerprints? How Psychedelics Influence Stress Physiology, Immunity, and Longevity Pathways episode artwork

EPISODE · Aug 7, 2026 · 27 MIN

#37 – Do Psychedelics Leave Biological Fingerprints? How Psychedelics Influence Stress Physiology, Immunity, and Longevity Pathways

from The Trip Lab · host Dr. Mary Ella Wood

Can a psychedelic experience leave measurable traces in the body long after the trip is over?In this episode, we explore emerging research on how psychedelics may influence:• DNA methylation and epigenetic signaling• The immune system, inflammation, and cytokines• The HPA axis, cortisol, and stress physiology• Neuroplasticity and lasting changes in brain connectivity• Cellular senescence, telomeres, oxidative stress, and longevity pathways• The bigger case for rethinking the mind-body dividePsychedelic science may be revealing something much larger than a drug effect: how experience itself becomes biology.The companion guide, full episode transcript and all studies and sources cited, is available on Substack.For more from me beyond the podcast, come hang out on Between Mind & Body on Substack, where I share full podcast transcripts and deeper companion content, essays, physician-created guides, emerging research, and the questions medicine has not quite answered yet.Substack: Between Mind & BodyInstagram: @drmaryellaLinkedIn: Mary Ella Wood, DO, ABOIMIf you enjoyed this episode, subscribing, sharing it with a friend, or leaving a review helps more than you know.

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Can a psychedelic experience leave measurable traces in the body long after the trip is over? In this episode, we explore emerging research on how psychedelics may influence: • DNA methylation and epigenetic signaling • The immune system, inflammation, and cytokines • The HPA axis, cortisol, and stress physiology • Neuroplasticity and lasting changes in brain connectivity • Cellular senescence, telomeres, oxidative stress, and longevity pathways • The bigger case for rethinking the mind-body ...

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#37 – Do Psychedelics Leave Biological Fingerprints? How Psychedelics Influence Stress Physiology, Immunity, and Longevity Pathways

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