371: What Founders Still Get Wrong in Crypto with Guest speaker William Quigley from WAX + Tether episode artwork

EPISODE · Mar 22, 2026 · 59 MIN

371: What Founders Still Get Wrong in Crypto with Guest speaker William Quigley from WAX + Tether

from Web3 with Sam Kamani · host Sam Kamani

In this episode, I sit down with William Quigley, co-founder of WAX and co-founder of Tether. We go deep into what is actually happening in crypto right now. We talk about stablecoins, gaming, startup strategy, market cycles, and why founders need insight more than hype. William shares hard-earned lessons from building early crypto products and explains where real value may come from next.This is a must-listen for founders, builders, and anyone trying to understand where Web3 is heading. We unpack why stablecoins matter, why most internal innovation fails, why altcoin speculation looks weaker this cycle, and what kinds of businesses still have a real shot at winning.Key points00:00 — Intro to the episode and why this conversation matters for founders01:24 — William’s path into crypto through virtual item trading in gaming04:23 — Why gaming platforms resist asset portability and user ownership05:26 — Why blockchain gaming adoption has been slower than expected07:26 — Prediction markets, speculation, and why they are still niche10:31 — How Tether started and the problem stablecoins were built to solve13:28 — Why Tether’s model worked and why algorithmic stablecoins failed17:07 — The future of stablecoins and the three models William sees winning20:30 — Will non-USD stablecoins grow over time?23:35 — Why FX fees are massive and how stablecoins can reduce that pain27:06 — What recent crypto events reveal about institutional vs retail interest29:14 — Why this cycle feels different and why altcoin season never fully arrived34:32 — Sam’s view on AI helping chains build actual apps, not just more infra37:42 — Why most internal innovation fails without real market insight44:28 — How to think about fear, greed, and crypto sentiment46:38 — If William started again today, what kind of business would he build?50:26 — Sam on AI, quantum computing, and selling tools in the next tech wave54:22 — Why timing matters as much as the idea itself56:09 — Institutional capital, long-term adoption, and what may come nextDisclaimerNothing mentioned in this podcast is investment advice and please do your own research.It would mean a lot if you can leave a review of this podcast on ApplePodcasts or Spotify and share this podcast with a friend.Be a guest on the podcast or contact us -⁠ https://www.web3pod.xyz/⁠

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371: What Founders Still Get Wrong in Crypto with Guest speaker William Quigley from WAX + Tether

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