EPISODE · Mar 26, 2024 · 25 MIN
39: Balancing Perfusion Process Development and Sustainability w/ Jochen Sieck - Part 1
from Smart Biotech Scientist | The CMC and Biomanufacturing Podcast for Bioprocess Development and Manufacturing Leaders · host David Brühlmann: Biotech Entrepreneur & Cell Culture Technology Innovation Aficionado
Explore perfusion processes and sustainability with our guest, Jochen Sieck, Director of Cell Culture Media and Process Development at Merck Life Science.Learn about the evolution of perfusion methodologies, its historical roots in addressing product stability, and its recent return to continuous and integrated manufacturing.Jochen discusses the economic and strategic reasons behind perfusion's resurgence, emphasizing the need for flexible, smaller-scale facilities.Key Learnings:Gain insight into the environmental impact of traditional facilities and the potential benefits of alternatives.Dive deep into the balance of cost, productivity, and sustainability in media consumption.Discover strategies for optimizing perfusion rates and sustainability.Get ready to expand your understanding of perfusion processes, sustainability, and the delicate dance between economics and environmental consciousness.Connect with Jochen Sieck:LinkedIn: https://www.linkedin.com/in/jochenbsieckACTIP Fellowship award: https://www.actip.org/fellowshipResources:Perfusion Cell Culture Processes for Biopharmaceuticals by Moritz Wolf, Jean-Marc Bielser, and Massimo Morbidelli: https://www.cambridge.org/core/books/perfusion-cell-culture-processes-for-biopharmaceuticals/5C650AD26D52B2435E7796D382ECE5DANext Step:Elevate your biologics development strategy — Schedule your free assessment now: https://bruehlmann-consulting.comOne bad CDMO decision can cost you two years and your Series A. If you're navigating tech transfer, CDMO selection, or IND prep, let's talk before it gets expensive. Two slots open this month.Support the show
What this episode covers
Explore perfusion processes and sustainability with our guest, Jochen Sieck, Director of Cell Culture Media and Process Development at Merck Life Science. Learn about the evolution of perfusion methodologies, its historical roots in addressing product stability, and its recent return to continuous and integrated manufacturing. Jochen discusses the economic and strategic reasons behind perfusion's resurgence, emphasizing the need for flexible, smaller-scale facilities. Key Learnings: Gain insi...
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39: Balancing Perfusion Process Development and Sustainability w/ Jochen Sieck - Part 1
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