EPISODE · Mar 26, 2024 · 24 MIN
39: Balancing Perfusion Process Development and Sustainability w/ Jochen Sieck - Part 1
from Smart Biotech Scientist | The CMC and Bioprocessing Podcast for Process Development and Manufacturing Leaders · host David Brühlmann: Biotech Entrepreneur & Cell Culture Technology Innovation Aficionado
Explore perfusion processes and sustainability with our guest, Jochen Sieck, Director of Cell Culture Media and Process Development at Merck Life Science. Learn about the evolution of perfusion methodologies, its historical roots in addressing product stability, and its recent return to continuous and integrated manufacturing. Jochen discusses the economic and strategic reasons behind perfusion's resurgence, emphasizing the need for flexible, smaller-scale facilities. Key Learnings: Gain insight into the environmental impact of traditional facilities and the potential benefits of alternatives. Dive deep into the balance of cost, productivity, and sustainability in media consumption. Discover strategies for optimizing perfusion rates and sustainability. Get ready to expand your understanding of perfusion processes, sustainability, and the delicate dance between economics and environmental consciousness. Connect with Jochen Sieck: LinkedIn: https://www.linkedin.com/in/jochenbsieck ACTIP Fellowship award: https://www.actip.org/fellowship Resources: Perfusion Cell Culture Processes for Biopharmaceuticals by Moritz Wolf, Jean-Marc Bielser, and Massimo Morbidelli: https://www.cambridge.org/core/books/perfusion-cell-culture-processes-for-biopharmaceuticals/5C650AD26D52B2435E7796D382ECE5DA Next Step: Elevate your biologics development strategy — Schedule your free assessment now: https://bruehlmann-consulting.com Free 5-day email course, The CMC Failure Chain: the five recurring CMC mistakes that put your promising program at risk → Get it here Support the show
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Explore perfusion processes and sustainability with our guest, Jochen Sieck, Director of Cell Culture Media and Process Development at Merck Life Science. Learn about the evolution of perfusion methodologies, its historical roots in addressing product stability, and its recent return to continuous and integrated manufacturing. Jochen discusses the economic and strategic reasons behind perfusion's resurgence, emphasizing the need for flexible, smaller-scale facilities. Key Learnings: Gain insi...
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39: Balancing Perfusion Process Development and Sustainability w/ Jochen Sieck - Part 1
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