390. Neuromod: How non-invasive ultrasound neuromodulation could change autoimmune disease treatment with Nishant Doctor of Surf Therapeutics

Omar Khateeb speaks with Nishant Doctor, Founder, CEO, and CTO of Surf Therapeutics, about the next frontier of neurotechnology: using ultrasound neuromodulation to target inflammation.Nishant breaks down the science behind the cholinergic anti-inflammatory pathway, why the splenic nerve may offer a more direct target than the vagus nerve, and how non-invasive stimulation could create a different treatment path for rheumatoid arthritis patients.The episode also covers capital efficiency, first-in-human studies, patient usability, autoimmune disease, and why Surf is focused on building a therapy that could be safer, easier, and more accessible than invasive alternatives.A powerful conversation on bioelectronic medicine, chronic disease, and the future of non-invasive MedTech.This podcast is for informational and educational purposes only and does not constitute financial, investment, legal, or medical advice. The views and opinions expressed by hosts and guests are their own and do not necessarily reflect those of State of MedTech LLC. Nothing discussed on this podcast should be interpreted as a recommendation to buy, sell, or hold any investment or security. Listeners should conduct their own due diligence and consult with a qualified financial advisor, attorney, or other professional before making any financial or investment decisions.Episode Breakdown00:00 How One Minute of Stimulation Can Reduce Inflammation01:34 Intro + Why Drug Alternatives Matter03:23 Nishant Doctor’s Journey Into Neuromodulation05:23 Neuromodulation vs Neurotechnology Explained08:15 Neuralink, BCI, and the Rise of NeuroTech09:07 Building Through Market Cycles13:37 The Origin Story of Surf Therapeutics15:23 Inflammation, Healthspan, and Chronic Disease17:52 The Science Behind the Anti-Inflammatory Pathway18:50 Why Vagus Nerve Stimulation Works20:18 Why Surf Chose a Non-Invasive Approach21:31 The Problem with Current Treatment Options22:44 Going Directly to the Splenic Nerve24:26 Vagus Nerve Side Effects Explained26:03 Biohacking, Longevity, and Vagus Nerve Devices27:15 How Surf’s Technology Works29:40 Capital Efficiency and Startup Execution32:02 Why Testing Beats Product Perfection33:58 Build Fast, Test Fast, Learn Fast37:20 Why Rheumatoid Arthritis Was the First Target39:38 The Rheumatoid Arthritis Opportunity40:02 Understanding Rheumatoid Arthritis41:38 Expanding Beyond a Single Disease43:31 The Future of Inflammation Therapy44:55 Why the Company is Called Surf46:16 Clinical Progress and Upcoming Milestones48:02 Strategic Interest and Future Opportunities48:38 OutroAre you a medtech CEO in need of some marketing help attracting investors, growing sales pipeline, and more? Go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠GrowMyMedtech.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to book time for a free analysis.Subscribe to our Youtube Channelhttps://www.youtube.com/@thestateofmedtechSubscribe to our LinkedIn Newsletterhttps://www.linkedin.com/newsletters/state-of-medtech-pod-7328860752952352770/Follow The State of MedTech onLinkedIn https://www.linkedin.com/company/thestateofmedtech/Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/stateofmedtech/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TikTok ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.tiktok.com/@stateofmedtechpodX https://x.com/stateofmedtechFacebook ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/stateofmedtechFollow Omar M. Khateeb onLinkedIn ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/okhateeb/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/omar.m.khateeb/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TikTok https://www.tiktok.com/@omar.m.khateebX ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https: https://x.com/OmarMKhateebFacebook ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/OmarMKhateeb#neurotech #neuromodulation #rheumatoidarthritis #medtech #healthcareinnovation