EPISODE · Jun 12, 2026 · 1H 6M
391: The Kaufmann Protocol — Why We Age and How to Stop It
from Base by Base · host Gustavo Barra
Dr. Sandra Kaufmann, The Kaufmann Anti-Aging Institute - Dr. Sandra Kaufmann — physician, scientist and athlete — set out to understand aging and fight it with science. This episode is a guided overview of her book, featured with the author's permission: why our cells age (mitochondria, genetic information systems, quality control and maintenance, immunity, and waste management) and the families of anti-aging molecules she reviews (resveratrol, astaxanthin, NAD, curcumin, metformin, melatonin and more) — framed as an informed, individualized approach rather than a quick fix. Key terms: aging, longevity, anti-aging molecules, cellular biology, Kaufmann Protocol. Study Highlights:The book maps aging onto cellular causes — declining mitochondria, genetic information systems, cellular quality control and maintenance, immune changes, and waste management — and then reviews the leading molecules and adjuvants that target these pathways. Dr. Kaufmann turns the science into the basis for an informed, personalized plan, stressing that it is not a diet or quick fix and that decisions about supplements should be made together with a physician. Conclusion:Aging has identifiable biological drivers, and a science-literate, individualized approach — discussed with a physician — can help people age more deliberately rather than passively. Presented as Dr. Kaufmann's perspective, featured with the author's permission. Title: The Kaufmann Protocol: Why We Age and How to Stop It Reference: Kaufmann, S.C. The Kaufmann Protocol: Why We Age and How to Stop It. Jacob Cerny (Ed.), Ross Goldstein (Illus.). Kaufmann Anti-Aging Institute, 2018. ISBN 978-0-692-08904-0. ISBN: 978-0-692-08904-0 License:This episode is a guided overview of the book "Why We Age and How to Stop It: The Kaufmann Protocol" by Dr. Sandra Kaufmann, featured and adapted with the kind permission of the author. Support:Base by Base – Stripe donations: https://donate.stripe.com/7sY4gz71B2sN3RWac5gEg00 Official website https://basebybase.com On PaperCast Base by Base you'll discover the latest in genomics, functional genomics, structural genomics, and proteomics. Episode link: https://basebybase.castos.com/episodes/kaufmann-protocol-why-we-age QC:This episode is a guided overview of the book "Why We Age and How to Stop It — The Kaufmann Protocol" by Dr. Sandra Kaufmann, featured with the author's kind permission and reviewed for editorial accuracy. QC Summary:- verdict: pass- review mode: book overview (author-authorized)- framing: presented as the author's perspective and synthesis- note: educational content only — not medical advice; decisions about supplements should be made with a physician
What this episode covers
Dr. Sandra Kaufmann, The Kaufmann Anti-Aging Institute - Dr. Sandra Kaufmann — physician, scientist and athlete — set out to understand aging and fight it with science. This episode is a guided overview of her book, featured with the author's permission: why our cells age (mitochondria, genetic information systems, quality control and maintenance, immunity, and waste management) and the families of anti-aging molecules she reviews (resveratrol, astaxanthin, NAD, curcumin, metformin, melatonin and more) — framed as an informed, individualized approach rather than a quick fix. Key terms: aging, longevity, anti-aging molecules, cellular biology, Kaufmann Protocol. Study Highlights:The book maps aging onto cellular causes — declining mitochondria, genetic information systems, cellular quality control and maintenance, immune changes, and waste management — and then reviews the leading molecules and adjuvants that target these pathways. Dr. Kaufmann turns the science into the basis for an informed, personalized plan, stressing that it is not a diet or quick fix and that decisions about supplements should be made together with a physician. Conclusion:Aging has identifiable biological drivers, and a science-literate, individualized approach — discussed with a physician — can help people age more deliberately rather than passively. Presented as Dr. Kaufmann's perspective, featured with the author's permission. Title: The Kaufmann Protocol: Why We Age and How to Stop It Reference: Kaufmann, S.C. The Kaufmann Protocol: Why We Age and How to Stop It. Jacob Cerny (Ed.), Ross Goldstein (Illus.). Kaufmann Anti-Aging Institute, 2018. ISBN 978-0-692-08904-0. ISBN: 978-0-692-08904-0 License:This episode is a guided overview of the book "Why We Age and How to Stop It: The Kaufmann Protocol" by Dr. Sandra Kaufmann, featured and adapted with the kind permission of the author. Support:Base by Base – Stripe donations: https://donate.stripe.com/7sY4gz71B2sN3RWac5gEg00 Official website https://basebybase.com On PaperCast Base by Base you'll discover the latest in genomics, functional genomics, structural genomics, and proteomics. Episode link: https://basebybase.castos.com/episodes/kaufmann-protocol-why-we-age QC:This episode is a guided overview of the book "Why We Age and How to Stop It — The Kaufmann Protocol" by Dr. Sandra Kaufmann, featured with the author's kind permission and reviewed for editorial accuracy. QC Summary:- verdict: pass- review mode: book overview (author-authorized)- framing: presented as the author's perspective and synthesis- note: educational content only — not medical advice; decisions about supplements should be made with a physician
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391: The Kaufmann Protocol — Why We Age and How to Stop It
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