395 — Dr. Nathan Bryan: Hormones, Heart & Skin—Surprising Roles for Nitric Oxide

Molecular-medicine expert Dr. Nathan Bryan explains how nitric oxide (NO) protects the endothelium, drives vasodilation, and influences energy, immunity, hormones, and longevity. He links stubborn hypertension and poor exercise tolerance to the microbiome–NO axis and outlines common NO killers—antiseptic mouthwashes and fluoride overuse, chronic PPIs, ultra-processed diets, and inactivity. We cover practical restores (movement, nutrient-dense food, targeted micronutrients, careful PPI weaning, ditching antiseptic rinses) and preview clinical work on NO-releasing lozenges for ischemic heart disease, approaches to improve cerebral blood flow and insulin signaling in cognitive decline, and topical NO for chronic wounds. Bryan also touches on food quality (glyphosate, soil health), hormone synergy with NO, and NO-based skincare that supports perfusion and collagen. Bottom line: rebuild NO, and the body’s own repair systems can finally do their job.(Educational only; not personal medical advice.)Guest BioNathan S. Bryan, PhD is a molecular medicine researcher and leading authority on nitric oxide (NO) biochemistry. Over two decades, he has mapped how the body generates and uses NO—and what happens when it doesn’t—publishing widely, authoring multiple books, and translating discoveries into products and late-stage drug trials. His work spans cardiovascular health, metabolism, neurocognition, wound healing, and skin biology, with a focus on restoring NO as a foundation for repair. Dr. Bryan speaks globally on NO and leads development of NO-based therapeutics targeting ischemic heart disease, Alzheimer’s disease, and non-healing ulcers. GET SOCIAL WITH US!🎧 Subscribe to BS Free MD for unfiltered insights on medicine, wellness, and everything in between.💬 Got thoughts or questions? DM us or drop a comment—we love hearing from you! [email protected] DISCLAIMEREverything in this podcast is for educational purposes only. It does not constitute the practice of medicine and we are not providing medical advice. No Physician-patient relationship is formed and anything discussed in this podcast does not represent the views of our employers. The Fine Print!All opinions expressed by the hosts or  guests in this episode are solely their opinion and are not to be used as specific medical advice.  The hosts,  May and Tim Hindmarsh MD, BS Free MD LLC, or any affiliates thereof are not under any obligation to update or correct any information provided in this episode. The guest's statements and opinions are subject to change without notice.Thanks for joining us! You are the reason we are here.  If you have questions, reach out to us at [email protected] or find Tim and I on Facebook and IG.Please check out our every growing website as well at bsfreemd.com (no www) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.