395. Is depression just a chemical imbalance? episode artwork

EPISODE · Mar 15, 2026 · 32 MIN

395. Is depression just a chemical imbalance?

from The Psychology of your 20s · host Alendra Zariñan

The idea that depression is caused by a “chemical imbalance” is one of the most widely accepted explanations in modern mental health ... but is it actually true? In this bonus episode, we unpack where the chemical imbalance theory came from, how it became the dominant narrative around depression, and why many researchers today believe the story is far more complicated. Including:  The academic and applied history of this theory  What research says about antidepressants vs placebo Why the “low serotonin” explanation may be too simple The psychological and social drivers of depression Why meaning, connection, and environment matter for mental health Why depression treatment often works best when it’s multi-layered Happy listening! Watch on Netflix Follow Jemma on Instagram: @jemmasbeg Follow the podcast on Instagram: @thatpsychologypodcast Subscribe on Substack: @thepsychologyofyour20s For business: [email protected]  The Psychology of your 20s is not a substitute for professional mental health help. If you are struggling, distressed or require personalised advice, please reach out to your doctor or a licensed psychologist.See omnystudio.com/listener for privacy information.

The idea that depression is caused by a “chemical imbalance” is one of the most widely accepted explanations in modern mental health ... but is it actually true? In this bonus episode, we unpack where the chemical imbalance theory came from, how it became the dominant narrative around depression, and why many researchers today believe the story is far more complicated. Including:  The academic and applied history of this theory  What research says about antidepressants vs placebo Why the “low serotonin” explanation may be too simple The psychological and social drivers of depression Why meaning, connection, and environment matter for mental health Why depression treatment often works best when it’s multi-layered Happy listening! Watch on Netflix Follow Jemma on Instagram: @jemmasbeg Follow the podcast on Instagram: @thatpsychologypodcast Subscribe on Substack: @thepsychologyofyour20s For business: [email protected]  The Psychology of your 20s is not a substitute for professional mental health help. If you are struggling, distressed or require personalised advice, please reach out to your doctor or a licensed psychologist.See omnystudio.com/listener for privacy information.

NOW PLAYING

395. Is depression just a chemical imbalance?

0:00 32:44

No transcript for this episode yet

We transcribe on demand. Request one and we'll notify you when it's ready — usually under 10 minutes.

Frequently Asked Questions

How long is this episode of The Psychology of your 20s?

This episode is 32 minutes long.

When was this The Psychology of your 20s episode published?

This episode was published on March 15, 2026.

What is this episode about?

The idea that depression is caused by a “chemical imbalance” is one of the most widely accepted explanations in modern mental health ... but is it actually true? In this bonus episode, we unpack where the chemical imbalance theory came from, how it...

Is there a transcript available for this episode?

Yes, a full transcript is available for this episode. You can read the complete transcript on the episode page.

Can I download this The Psychology of your 20s episode?

Yes, you can download this episode by clicking the download button on the episode player, or subscribe to the podcast in your preferred podcast app for automatic downloads.
URL copied to clipboard!