3I/ATLAS Explained, Forensic Fingerprints & Alzheimer’s Breakthrough (EP. 18) episode artwork

EPISODE · Nov 27, 2025 · 1H 27M

3I/ATLAS Explained, Forensic Fingerprints & Alzheimer’s Breakthrough (EP. 18)

from From First Principles · host Krishna Choudhary and Lester Nare

Hosted by Lester Nare and Krishna Choudhary, this episode spans astrophysics, forensic chemistry, and neuroimmunology. We begin with a deep dive into 3I/ATLAS, only the third confirmed interstellar object to ever pass through our solar system — larger and stranger than ‘Oumuamua and Borisov, with new imagery released as NASA reopened operations. Then we break down a true-crime forensic breakthrough from Maynooth University that reveals how to recover fingerprints from fired bullet casings — a technique that could radically accelerate criminal investigations. And we close with a Max Planck Institute discovery identifying a regulatory microglial state in the brain that may finally clarify why Alzheimer’s develops — and how immune dysfunction, not just plaques, drives the disease.SummaryThe third interstellar visitor — 3I/ATLAS joins ‘Oumuamua and Borisov as only the third object ever observed entering the solar system from interstellar space, with new NASA imagery revealing structure, trajectory, and compositional clues.A forensic chemistry breakthrough — researchers at Maynooth University develop a technique to retrieve latent fingerprints from fired shell casings, combining heat-stable organic residues with spectroscopic imaging.A new model of Alzheimer’s — Max Planck Institute scientists uncover a microglial “regulatory” state (a T-reg–like analogue) activated through CD28-dependent pathways, reshaping how the field thinks about plaques, neuroinflammation, and therapeutic targets.Show Notes3I/ATLAS — Interstellar Object Updates (NASA / JPL)Forensic Chemistry: Fingerprints on Fired Casings (Maynooth University)Alzheimer’s Microglia Study — Max Planck Institute / Univ. of Cologne

Episode metadata supplied by the publisher feed · Published Nov 27, 2025

Embed this episode

Ready to play

3I/ATLAS Explained, Forensic Fingerprints & Alzheimer’s Breakthrough (EP. 18)

0:00 1:27:30

No transcript for this episode yet

We transcribe on demand. Request one and we'll notify you when it's ready — usually under 10 minutes.

No similar episodes found.

No similar podcasts found.

Frequently Asked Questions

How long is this episode of From First Principles?

This episode is 1 hour and 27 minutes long.

When was this From First Principles episode published?

This episode was published on November 27, 2025.

Can I download this From First Principles episode?

Yes. Use the download control on the episode player to save the publisher-provided media file.
URL copied to clipboard!