4 14 2025

Hi, This Week in Medicine, we will be discussing

 New England Journal of Medicine

Extended Reduced-Dose Apixaban for Cancer-Associated Venous Thromboembolism

Endovascular Treatment for Stroke Due to Occlusion of Medium or Distal Vessels

Endovascular Treatment of Stroke Due to Medium-Vessel Occlusion

Dapagliflozin in Patients Undergoing Transcatheter Aortic-Valve Implantation

Assessment of a Polygenic Risk Score in Screening for Prostate Cancer

  Journal of  American Medical Association

Invasive Group A Streptococcal Infections in 10 US States

 Annals of Internal Medicine

Insurer-Level Estimates of Revenue From Differential Coding in Medicare Advantage

  British Medical Journal

Evolution of reported patient and public involvement over time in randomised controlled trials in major medical journals and in their protocols

  Lancet

Effect of digital adherence technologies on treatment outcomes in people with drug-susceptible tuberculosis: four pragmatic, cluster-randomised trials

  Cancer Journal for Clinicians

Cancer statistics for African American and Black people, 2025

 Journal of Clinical Oncology

Minimal Residual Disease–Based End Point for Accelerated Assessment of Clinical Trials in Multiple Myeloma: A Pooled Analysis of Individual Patient Data From Multiple Randomized Trials

  journal of Hepatology

Association of metabolic signatures of air pollution with MASLD: Observational and Mendelian randomization study

 Gastroenterology

Glepaglutide, a Long-Acting Glucagon-like Peptide-2 Analogue, Reduces Parenteral Support in Patients With Short Bowel Syndrome: A Phase 3 Randomized Controlled Trial

 Clinical Gastroenterology

Histological Outcomes of Pharmacological Interventions in Eosinophilic Esophagitis for Adults and Children: A Network Meta-analysis of Randomized Controlled Trials

 Rheumatology 

Safety of Avacopan for the Treatment of Antineutrophil Cytoplasmic Antibody–Associated Vasculitis: Combined Data From Three Clinical Trials

  Journal of Clinical Rheumatology 

Age-Related Differences Between Juvenile and Adult Autoimmune Inflammatory Myopathies

  Circulation

Evidence-Based Application of Natriuretic Peptides in the Evaluation of Chronic Heart Failure With Preserved Ejection Fraction in the Ambulatory Outpatient Setting

  Journals of the American College of Cardiology

Cardiac Troponins and Cardiovascular Disease Risk Prediction: An Individual-Participant-Data Meta-Analysis

  JAMA Cardiology

Default Bulk Ordering and Text Messaging to Enhance Outreach for Lipid ScreeningA Randomized Clinical Trial

 Journal of Clinical Endocrinology & Metabolism

MBX 2109, A Once-Weekly Parathyroid Hormone Replacement Therapy Prodrug: Phase 1, First-In-Human, Randomized Trial 

  Diabetes care

Diabetes Risk After Treatment for Childhood and Young Adult Cancer 

  Neurology

Neurodegeneration and Demyelination in the Multiple Sclerosis Spinal Cord: Clinical, Pathological, and 7T MRI Perspectives

  Chest

Estimation of Expiratory Function in Infants With Passive Expiration From Total Lung Capacity

  The American Journal of Respiratory and Critical Care Medicine

Temporal Exploration of Chronic Obstructive Pulmonary Disease Phenotypes: Insights from the COPDGene and SPIROMICS Cohorts

  Kidney International reports

Real-Life Data of 2-Year Lumasiran Use in the DAILY-LUMA Cohort

Systematic Review of the Effects of Iron on Cardiovascular, Kidney, and Safety Outcomes in Patients With CKD