4 22 2024

Hi, This Week in Medicine, we will be discussing

New England Journal of Medicine

Overall Survival with Adjuvant Pembrolizumab in Renal-Cell Carcinoma

Beta-Blockers after Myocardial Infarction and Preserved Ejection Fraction

Microaxial Flow Pump or Standard Care in Infarct-Related Cardiogenic Shock

Semaglutide in Patients with Obesity-Related Heart Failure and Type 2 Diabetes

  Journal of  American Medical Association

Serious Bleeding in Patients With Atrial Fibrillation Using Diltiazem With Apixaban or Rivaroxaban

Non–High-Density Lipoprotein Cholesterol Levels From Childhood to Adulthood and Cardiovascular Disease Events

 Annals of Internal Medicine

Deep Learning to Estimate Cardiovascular Risk From Chest Radiographs: A Risk Prediction Study

  Nature Medicine

Development and validation of a new algorithm for improved cardiovascular risk prediction

  British Medical Journal

Temporal trends in lifetime risks of atrial fibrillation and its complications between 2000 and 2022: Danish, nationwide, population based cohort study

  Lancet

Patient, family caregiver, and economic outcomes of an integrated screening and novel stepped collaborative care intervention in the oncology setting in the USA (CARES): a randomised, parallel, phase 3 trial

  Journal of Clinical Oncology

Phase III, Randomized Study of Atezolizumab Plus Bevacizumab and Chemotherapy in Patients With EGFR- or ALK-Mutated Non–Small-Cell Lung Cancer (ATTLAS, KCSG-LU19-04)

  journal of Hepatology

Efficient formation and maintenance of humoral and CD4 T-cell immunity targeting the viral capsid in acute-resolving hepatitis E infection

A new clinical and prognostic characterization of the patterns of decompensation of cirrhosis

Clinical Gastroenterology

Statins Are Associated With a Decreased Risk of Severe Liver Disease in Individuals With Noncirrhotic Chronic Liver Disease

Accuracy of the Enhanced Liver Fibrosis Test in Patients With Type 2 Diabetes Mellitus and Its Clinical Implications

Histologic Activity in Inflammatory Bowel Disease and Risk of Serious Infections: A Nationwide Study

The Diagnostic Performance of Fecal Immunochemical Tests for Detecting Advanced Neoplasia at Surveillance Colonoscopy

 Clinical Infectious Diseases

Clinical Outcomes of Patients With Nontyphoidal SalmonellaInfections by Isolate Resistance—Foodborne Diseases Active Surveillance Network, 10 US Sites, 2004–2018 

Clinical Impact of Multiplex Molecular Diagnostic Testing in Children With Acute Gastroenteritis Presenting to an Emergency Department: A Multicenter Prospective Study 

Timing and Predictors of Loss of Infectivity Among Healthcare Workers With Mild Primary and Recurrent COVID-19: A Prospective Observational Cohort Study

  Journal of infectious Diseases

The Effects of Human Immunodeficiency Virus Type 1 (HIV-1) Antigen-Expanded Specific T-Cell Therapy and Vorinostat on Persistent HIV-1 Infection in People With HIV on Antiretroviral Therapy

 Arthritis and Rheumatology

Towards the Lowest Efficacious Dose: Results From a Multicenter Noninferiority Randomized Open-Label Controlled Trial Assessing Tocilizumab or Abatacept Injection Spacing in Rheumatoid Arthritis in Remission

American College of Cardiology

Preventive Coronary Intervention on Stenosis With Functionally Insignificant Vulnerable Plaque

 Journals of the American College of Cardiology

Water Conservation Overrides Osmotic Diuresis During SGLT2 Inhibition in Patients With Heart Failure

 Journal of Clinical Endocrinology & Metabolism

Discontinuation of Drug Treatment in Cushing's Disease Not Cured by Pituitary Surgery

Dasiglucagon for the Treatment of Congenital Hyperinsulinism: A Randomized Phase 3 Trial in Infants and Children

  Neurology:

Trends in Cognitive Function Before and After Diabetes Onset: The China Health and Retirement Longitudinal Study

Statin Therapy for Secondary Prevention in Ischemic Stroke Patients With Cerebral Microbleeds

 Chest

Longitudinal Effects of Elexacaftor/Tezacaftor/Ivacaftor

Etiology-Based Prognosis of Extracorporeal CPR Recipients After Out-of-Hospital Cardiac Arrest

Hospital Policy Variation in Addressing Decisions to Withhold and Withdraw Life-Sustaining Treatment

 The American Journal of Respiratory and Critical Care Medicine

Heterogeneity of Benefit from Earlier Time-to-Antibiotics for Sepsis

 Clinical Journal of American Society of Nephrology

Association of Bioimpedance Parameters with Increases in Blood Pressure during Hemodialysis

Drug-Coated Balloon Angioplasty for Dysfunctional Arteriovenous Hemodialysis Fistulae: A Randomized Controlled Trial

  Kidney International reports

Patient Perspectives of Center-Specific Reporting in Kidney Failure Care: An Australian Qualitative Study

Features of Postpartum Hemorrhage-Associated Thrombotic Microangiopathy and Role of Short-Term Complement Inhibition