4 22 2024

Hi, This Week in Medicine, we will be discussingNew England Journal of MedicineOverall Survival with Adjuvant Pembrolizumab in Renal-Cell Carcinoma Beta-Blockers after Myocardial Infarction and Preserved Ejection Fraction Microaxial Flow Pump or Standard Care in Infarct-Related Cardiogenic Shock Semaglutide in Patients with Obesity-Related Heart Failure and Type 2 Diabetes  Journal of  American Medical AssociationSerious Bleeding in Patients With Atrial Fibrillation Using Diltiazem With Apixaban or Rivaroxaban Non–High-Density Lipoprotein Cholesterol Levels From Childhood to Adulthood and Cardiovascular Disease Events Annals of Internal MedicineDeep Learning to Estimate Cardiovascular Risk From Chest Radiographs: A Risk Prediction Study  Nature MedicineDevelopment and validation of a new algorithm for improved cardiovascular risk prediction  British Medical JournalTemporal trends in lifetime risks of atrial fibrillation and its complications between 2000 and 2022: Danish, nationwide, population based cohort study  LancetPatient, family caregiver, and economic outcomes of an integrated screening and novel stepped collaborative care intervention in the oncology setting in the USA (CARES): a randomised, parallel, phase 3 trial  Journal of Clinical Oncology Phase III, Randomized Study of Atezolizumab Plus Bevacizumab and Chemotherapy in Patients With EGFR- or ALK-Mutated Non–Small-Cell Lung Cancer (ATTLAS, KCSG-LU19-04)  journal of HepatologyEfficient formation and maintenance of humoral and CD4 T-cell immunity targeting the viral capsid in acute-resolving hepatitis E infection A new clinical and prognostic characterization of the patterns of decompensation of cirrhosis Clinical GastroenterologyStatins Are Associated With a Decreased Risk of Severe Liver Disease in Individuals With Noncirrhotic Chronic Liver Disease Accuracy of the Enhanced Liver Fibrosis Test in Patients With Type 2 Diabetes Mellitus and Its Clinical Implications Histologic Activity in Inflammatory Bowel Disease and Risk of Serious Infections: A Nationwide Study The Diagnostic Performance of Fecal Immunochemical Tests for Detecting Advanced Neoplasia at Surveillance Colonoscopy Clinical Infectious DiseasesClinical Outcomes of Patients With Nontyphoidal SalmonellaInfections by Isolate Resistance—Foodborne Diseases Active Surveillance Network, 10 US Sites, 2004–2018  Clinical Impact of Multiplex Molecular Diagnostic Testing in Children With Acute Gastroenteritis Presenting to an Emergency Department: A Multicenter Prospective Study  Timing and Predictors of Loss of Infectivity Among Healthcare Workers With Mild Primary and Recurrent COVID-19: A Prospective Observational Cohort Study  Journal of infectious DiseasesThe Effects of Human Immunodeficiency Virus Type 1 (HIV-1) Antigen-Expanded Specific T-Cell Therapy and Vorinostat on Persistent HIV-1 Infection in People With HIV on Antiretroviral Therapy Arthritis and RheumatologyTowards the Lowest Efficacious Dose: Results From a Multicenter Noninferiority Randomized Open-Label Controlled Trial Assessing Tocilizumab or Abatacept Injection Spacing in Rheumatoid Arthritis in Remission American College of CardiologyPreventive Coronary Intervention on Stenosis With Functionally Insignificant Vulnerable Plaque Journals of the American College of CardiologyWater Conservation Overrides Osmotic Diuresis During SGLT2 Inhibition in Patients With Heart Failure Journal of Clinical Endocrinology & MetabolismDiscontinuation of Drug Treatment in Cushing's Disease Not Cured by Pituitary Surgery Dasiglucagon for the Treatment of Congenital Hyperinsulinism: A Randomized Phase 3 Trial in Infants and Children  Neurology:Trends in Cognitive Function Before and After Diabetes Onset: The China Health and Retirement Longitudinal Study Statin Therapy for Secondary Prevention in Ischemic Stroke Patients With Cerebral Microbleeds ChestLongitudinal Effects of Elexacaftor/Tezacaftor/Ivacaftor Etiology-Based Prognosis of Extracorporeal CPR Recipients After Out-of-Hospital Cardiac Arrest Hospital Policy Variation in Addressing Decisions to Withhold and Withdraw Life-Sustaining Treatment The American Journal of Respiratory and Critical Care MedicineHeterogeneity of Benefit from Earlier Time-to-Antibiotics for Sepsis Clinical Journal of American Society of NephrologyAssociation of Bioimpedance Parameters with Increases in Blood Pressure during Hemodialysis Drug-Coated Balloon Angioplasty for Dysfunctional Arteriovenous Hemodialysis Fistulae: A Randomized Controlled Trial  Kidney International reportsPatient Perspectives of Center-Specific Reporting in Kidney Failure Care: An Australian Qualitative Study Features of Postpartum Hemorrhage-Associated Thrombotic Microangiopathy and Role of Short-Term Complement Inhibition