4 8 2024

Hi, This Week in Medicine, we will be discussing  New England Journal of MedicineOmitting Axillary Dissection in Breast Cancer with Sentinel-Node Metastases Trial of Lixisenatide in Early Parkinson’s Disease Nirmatrelvir for Vaccinated or Unvaccinated Adult Outpatients with Covid-19 Pragmatic Trial of Hospitalization Rate in Chronic Kidney Disease Journal of  American Medical AssociationProstate-Specific Antigen Screening and 15-Year Prostate Cancer Mortality: A Secondary Analysis of the CAP Randomized Clinical Trial Single Ascending and Multiple-Dose Trial of Zerlasiran, a Short Interfering RNA Targeting Lipoprotein(a)  Annals of Internal MedicineAssociation of Low Glomerular Filtration Rate With Adverse Outcomes at Older Age in a Large Population With Routinely Measured Cystatin C  Nature MedicinePersonalized neoantigen vaccine and pembrolizumab in advanced hepatocellular carcinoma: a phase 1/2 trial British Medical JournalUse of progestogens and the risk of intracranial meningioma: national case-control study LancetCoronary sinus reducer for the treatment of refractory angina (ORBITA-COSMIC): a randomised, placebo-controlled trial Journal of Clinical Oncology Lenvatinib Plus Pembrolizumab Versus Sunitinib in First-Line Treatment of Advanced Renal Cell Carcinoma: Final Prespecified Overall Survival Analysis of CLEAR, a Phase III Study  journal of Hepatology Preventing liver disease with policy measures to tackle alcohol consumption and obesity: The HEPAHEALTH II study Effects of tetrathiomolybdate on copper metabolism in healthy volunteers and in patients with Wilson disease  Clinical GastroenterologyThe Index of Severity for Eosinophilic Esophagitis (I-SEE) Reflects Longitudinal Clinicopathologic Changes in Children Alcoholic Foamy Degeneration, an Entity Resembling Alcohol-Associated Hepatitis: Diagnosis, Prognosis, and Molecular Profiling Modified-Release Phosphatidylcholine (LT-02) for Ulcerative Colitis: Two Double-Blind, Randomized, Placebo-Controlled Trials Quality of Life and Bidirectional Gut-Brain Interactions in Irritable Bowel Syndrome From Adolescence to Adulthood Clinical liver diseaseAcceptability of hepatitis C screening and treatment during pregnancy in pregnant women in Egypt, Pakistan, and Ukraine: A cross-sectional survey  Clinical Infectious DiseasesIs Short-Course Antibiotic Therapy Suitable for Pseudomonas aeruginosa Bloodstream Infections in Onco-hematology Patients With Febrile Neutropenia? Results of a Multi-institutional Analysis Bartonella quintana Endocarditis: A Systematic Review of Individual Cases Socioeconomic and Demographic Risk Factors for SARS-CoV-2 Seropositivity Among Healthcare Workers in a UK Hospital: A Prospective Cohort Study  Journal of infectious DiseasesEffectiveness of BNT162b2 BA.4/5 Bivalent mRNA Vaccine Against Symptomatic COVID-19 Among Immunocompetent Individuals Testing at a Large US Retail Pharmacy  Journal of Clinical Rheumatology Transition From Pediatric to Adult Rheumatology Care: An Exploratory Study From Latin America  Arthritis and RheumatologyPoly-Refractory Rheumatoid Arthritis: An Uncommon Subset of Difficult to Treat Disease With Distinct Inflammatory and Noninflammatory Phenotypes  CirculationClinical and Prognostic Implications of Right Ventricular Uptake on Bone Scintigraphy in Transthyretin Amyloid Cardiomyopathy American College of Cardiology Journals of the American College of CardiologyVariation in Health Status With Invasive vs Conservative Management of Chronic Coronary Disease Journal of Clinical Endocrinology & MetabolismEffect and Interactions of BRAF on Lymph Node Metastasis in Papillary Thyroid Carcinoma With Hashimoto Thyroiditi  Metabolic Profiles of Type 2 Diabetes and Their Association With Renal Complications  Next we will be discussing articles  from Neurology:Remote Ischemic Conditioning With Medical Management or Reperfusion Therapy for Acute Ischemic Stroke: A Systematic Review and Meta-Analysis Statin Initiation and Risk of Incident Alzheimer Disease and Cognitive Decline in Genetically Susceptible Older Adults  ChestUse of Quantitative CT Imaging to Identify Bronchial Thermoplasty RespondersIndividual Risk Factors of PM2.5 Associated With Wintertime Mortality in Urban Patients With COPD High-Resolution CT Scan Fibrotic Patterns in Stage IV Pulmonary Sarcoidosis The American Journal of Respiratory and Critical Care MedicineAntimicrobial Drug Penetration Is Enhanced by Lung Tissue Inflammation and Injury Clinical Journal of American Society of Nephrology.Strategies to Guide Preemptive Waitlisting and Equity in Waittime Accrual by Race/Ethnicity Association of eGFR and Albuminuria with Venous Thromboembolism  Kidney International reportsAcute Kidney Injury Duration and 20-Year Risks of CKD and Cardiovascular Disease Systematic Review of Women Leading and Participating in Nephrology Randomized Clinical Trials