EPISODE · Mar 28, 2024 · 14 MIN
40: Balancing Perfusion Process Development and Sustainability w/ Jochen Sieck - Part 2
from Smart Biotech Scientist | The CMC and Biomanufacturing Podcast for Bioprocess Development and Manufacturing Leaders · host David Brühlmann: Biotech Entrepreneur & Cell Culture Technology Innovation Aficionado
Explore the intricate world of perfusion and its sustainability challenges in the part 2 of this episode. Dive into the operational side of managing vast quantities of media production and storage, and discover smart strategies to address these challenges.Jochen Sieck, Director of Cell Culture Media and Process Development at Merck Life Science, discusses the distinction between facility designs for batch and perfusion bioreactors, shedding light on the need for extensive tank farms to support perfusion.Key Insights:Explore the success of automated perfusion media preparation at the lab scale and its scaling up to a 500L capacity.Discover how advancements in small-scale perfusion operations are supercharging the perfusion process development.Get practical steps for developing a cost-efficient perfusion process.Tune in to discover how perfusion processes are revolutionizing the biotech industry and contributing to a more sustainable future.Connect with Jochen Sieck:LinkedIn: https://www.linkedin.com/in/jochenbsieckACTIP Fellowship award: https://www.actip.org/fellowshipResources:Perfusion Cell Culture Processes for Biopharmaceuticals by Moritz Wolf, Jean-Marc Bielser, and Massimo Morbidelli: https://www.cambridge.org/core/books/perfusion-cell-culture-processes-for-biopharmaceuticals/5C650AD26D52B2435E7796D382ECE5DANext Step:Elevate your biologics development strategy — Schedule your free assessment now: https://bruehlmann-consulting.comSupport the show
What this episode covers
Explore the intricate world of perfusion and its sustainability challenges in the part 2 of this episode. Dive into the operational side of managing vast quantities of media production and storage, and discover smart strategies to address these challenges. Jochen Sieck, Director of Cell Culture Media and Process Development at Merck Life Science, discusses the distinction between facility designs for batch and perfusion bioreactors, shedding light on the need for extensive tank farms to suppo...
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40: Balancing Perfusion Process Development and Sustainability w/ Jochen Sieck - Part 2
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