#444 Macrocytosis, Hemolytic Anemia, Myelodysplastic Syndrome

Recorded LIVE! At Johns Hopkins Internal Medicine Grand RoundsStep up your anemia game as we explore the causes and diagnostic approach for macrocytic anemia, what to do with a reticulocyte count, the differential diagnosis for hemolytic anemia, the significance of the direct antiglobulin test, and diagnosis and management pearls for autoimmune hemolytic anemia (AIHA) and myelodysplastic syndrome (MDS). Plus, common questions and concerns regarding folate supplementation and the use of bone marrow biopsies. We’re joined by hematologist and pun enthusiast Dr. Rakhi Naik MD, MHS, @redcell_doc @hopkinsheme. Claim CME for this episode at curbsiders.vcuhealth.org!Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CMEShow Segments 00:00 Intro and Guest intro 05:53 Case 1: Elise - Macrocytic Anemia 14:59 Case 2: Jane - Hemolytic Anemia 23:24 Testing for Underlying Causes of Autoimmune Hemolytic Anemia 24:40 Association of Autoimmune Hemolytic Anemia with Lymphomas 25:10 Autoimmune Hemolytic Anemia: Diagnosis and Treatment 26:06 Management Approach for Autoimmune Hemolytic Anemia 27:30 Considerations for Outpatient Treatment of Autoimmune Hemolytic Anemia 28:18 Clotting Risk in Autoimmune Hemolytic Anemia 29:20 Treatment Options for Autoimmune Hemolytic Anemia 30:42 Long-Term Prognosis and Recurrence of Autoimmune Hemolytic Anemia 33:32 Diagnostic Challenges in Myelodysplastic Syndrome 35:00 Considerations for Folate Supplementation 36:24 Factors to Consider in the Management of Myelodysplastic Syndrome 39:30 When to Perform a Bone Marrow Biopsy in Myelodysplastic Syndrome 41:25 Shared Decision-Making in the Treatment of Myelodysplastic Syndrome Credits Writer and Producer: Matthew Watto MD, FACP Show Notes: Matthew Watto MD, FACP Cover Art and Infographic: Matthew Watto MD, FACP Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP    Reviewer: Fatima Syed MD, MSc Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP Technical Production: PodPaste Guest: Rakhi P. Naik MD, MHS Sponsor: Beginly HealthVisit beginlyhealth.com/curbsiders job matching platform for every Physician and Advanced Practice Clinician, from training to practice.Sponsor: FreedYou can try Freed for free right now by going to freed.ai. And listeners of Curbsiders can use code CURB50 for $50 off their first month.Sponsor: BabbelGet up to 60% off your Babbel subscription, for a limited time, at Babbel.com/CURB.