464. 斯坦福科学家发现狼疮与EB病毒关联 episode artwork

EPISODE · Nov 17, 2025 · 15 MIN

464. 斯坦福科学家发现狼疮与EB病毒关联

from 知为谁 · host 知为谁

斯坦福医学院的科学家们发现了一种与狼疮相关的常见病毒,该研究详细介绍了爱泼斯坦-巴尔病毒(EBV)与这种慢性自身免疫性疾病之间的关系。研究表明,近乎所有人携带的EBV能够将受感染的B细胞转化为“邪恶的监督者”,从而重新编程其他免疫细胞来攻击人体组织,这被认为是百分之百的狼疮病例的原因。这项工作解释了EBV如何激活B细胞中的特定基因,导致产生针对细胞核成分的抗体,这是狼疮的标志。研究人员强调了EBV在极少数B细胞中的存在如何在狼疮患者中急剧增加,并提出了针对EBV或通过消除受感染B细胞来治疗狼疮的未来方向。此发现于2025年11月12日发表在《科学转化医学》上,被该研究的资深作者认为是其职业生涯中最具影响力的发现。内容来源:https://med.stanford.edu/news/all-news/2025/11/lupus-epstein-barr.html

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464. 斯坦福科学家发现狼疮与EB病毒关联

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