47: GLP-1's - What they do, who they're for, food noise, and more w/ Dr. Christle Guevarra episode artwork

EPISODE · Jun 16, 2026 · 1H 7M

47: GLP-1's - What they do, who they're for, food noise, and more w/ Dr. Christle Guevarra

from Lowering the Barrier · host Alex Thieme

If you've been wondering whether a GLP-1 might be right for you - but the fear and stigma around them have made you hesitate - this one's for you.It's a judgment-free conversation with Dr. Christle Guevarra, who comes at these medications from three angles at once: the doctor who prescribes them, the lifelong athlete who trains hard, and the patient who spent decades struggling before she ever tried one. A board-certified family and sports medicine physician and the traveling team physician for U.S. Figure Skating, she brings a balance of logic and empathy that suited this conversation perfectly.We cover the questions actually keeping people on the fence: what a GLP-1 does in your body, how to tell a genuine candidate from a vanity prescription, and the safety concerns everyone's anxious about - separating what's well-documented from what's just internet noise.We get into muscle loss, how to eat and train if you do start, whether it's a short-term tool or a lifelong medication, the real risks of the gray market, and the shame so many people carry about needing help at all. The goal isn't to talk you into it or out of it. It's to give you the honest information you need to make your own call - and to walk into your doctor's office knowing exactly what to ask.Timestamps:00:00 Introduction2:00 Burnout and the “arrival fallacy”12:00 What a GLP-1 is and how it works15:00 Food noise21:00 Semaglutide vs tirzepatide24:00 Who’s a candidate?31:00 How to eat (and dose) on a GLP-135:00 Safety: what’s real and what’s vibes40:00 How to prevent muscle loss48:00 Short or long-term medication53:00 Alcohol aversion, addiction research1:00:00 Retatrutide and the dangers of buying it overseas1:04:00 Final takeaway and where to find ChristleWhere to find Dr. ChristleDr. Christle Website: https://drchristle.com/Dr. Christle Instagram: https://www.instagram.com/dr.christle/My LinksWebsite: ⁠https://www.alexthiemefitness.com/⁠Instagram: ⁠https://www.instagram.com/alexthiemefitness/⁠TikTok: ⁠https://www.tiktok.com/@alexthiemefitness⁠Join my email list: ⁠https://www.alexthiemefitness.com/email⁠If you loved this episode, please follow/subscribe and give a 5 star review! Thank you!Bonus points - share it with a friend who might enjoy the show.

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47: GLP-1's - What they do, who they're for, food noise, and more w/ Dr. Christle Guevarra

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