#473 Dr Dwayne Jackson - Reclassifying PCOS to PMOS, What This Means episode artwork

EPISODE · May 28, 2026 · 48 MIN

#473 Dr Dwayne Jackson - Reclassifying PCOS to PMOS, What This Means

from Lift Free And Diet Hard with Andrew Coates · host Andrew Coates

Dr Dwayne Jackson returns to break down the implications of the reclassification of PCOS to PMOS (Polyendocrine Metabolic Ovarian Syndrome).Including:What the reclassification meansWhy it’s important and helpful for outcomesHow it affects careDo GLP-1 medications help in PMOSDwayne also explains:The newest updates about the triple agonist Retatrutide research and what this meansReconciling anecdotal claims against varying degrees of — and sometimes limited — research on peptidesThe potential risks of using “grey market” peptidesWhat the changes in US peptide regulatory policy mean for drug development and accessThoughts on the proliferation of influencers marketing peptidesSome thoughts on the bio-psycho-social modelAnd much moreInstagram: @drdnjacksonCHAPTERS01:10 PCOS Renamed to PMOS02:35 Why the Old Name Failed05:23 Causes and Genetics07:55 Lifestyle and Symptoms10:14 Sponsor Break – Just Bite Me Meals11:21 Identity and Reframing13:22 Clinical Care and Advocacy15:51 Action Steps: Diet and Training20:57 GLP-1s and PMOS22:50 Retatrutide Update26:54 Peptides: Evidence vs Hype30:07 Neuropeptide Y Cautionary Tale32:45 Navigating Risk and Incentives36:44 Sponsor Break – TrainHeroic38:24 Peptide Regulation and Politics41:34 Longevity Pyramid Explained46:27 The Biopsychosocial PMOS Framework48:00 Wrap Up and Where To Find DwayneSUPPORT THE SHOWIf this episode helped you better understand PMOS, GLP-1 medications, peptides, or evolving metabolic health science, you can support the show by:Subscribing and checking out more episodesSharing it on social media (tag me and I’ll respond)Sending it to someone interested in hormones, metabolism, or evidence-based health careFOLLOW ANDREW COATESInstagram: @andrewcoatesfitnesshttps://www.andrewcoatesfitness.comPARTNERS AND RESOURCESRP Strength App (use code COATESRP)https://www.rpstrength.com/coatesJust Bite Me Meals (use code ANDREWCOATESFITNESS for 10% off)https://justbitememeals.comMacrosFirst – FREE Premium TrialDownload MacrosFirst and during setup select ANDREWKNKG Bags (15% off)https://www.knkg.com/Andrew59676Versa Grippshttps://www.versagripps.com/andrewcoatesTRAINHEROIC – FREE 90-Day Trialhttps://www.trainheroic.com/liftfreeReply to the email you receive (or email [email protected]) and let them know Andrew sent you

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#473 Dr Dwayne Jackson - Reclassifying PCOS to PMOS, What This Means

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