474 | What interventions have the best evidence for down-regulating pain sensitivity (breath, sleep, graded exposure, strength, walking) episode artwork

EPISODE · Sep 7, 2026 · 24 MIN

474 | What interventions have the best evidence for down-regulating pain sensitivity (breath, sleep, graded exposure, strength, walking)

from The Optimal Body · host Dr Jen Fraboni, Dr Dom Fraboni

In this episode of the Optimal Body Podcast, doctors of physical therapy Doc Jen and Doctor Dom explore evidence-based strategies to reduce chronic pain sensitivity. They describe chronic pain sensitivity as a "volume knob" in the nervous system that can be turned down through five key interventions: aerobic exercise, strength training, improved sleep, cognitive behavioral therapy, and graded exposure to feared movements. Each approach targets pain from physical and psychological angles. The hosts also highlight breathwork as a bonus tool for managing acute pain flares, encouraging listeners to combine these strategies for lasting relief.Needed Discount:Jen trusted Needed Supplements for fertility, pregnancy, and beyond! Support men and women’s health with vitamins, Omega-3, and more. Used by 6,000+ pros. Use code OPTIMAL for 20% off at checkout!We Think You'll Love:Free Week of Jen HealthJen’s InstagramDom’s InstagramYouTube ChannelWhat You'll Learn:1:48 Introduction to Pain Sensitivity3:23 Aerobic Exercise8:34 Exercise Training12:48 Sleep Interventions15:28 Cognitive Behavioral Approaches18:59 Graded Exposure20:42 The Role of BreathworkFor full show notes and resources visit: https://jen.health/podcast/474 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Episode metadata supplied by the publisher feed · Published Sep 7, 2026

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In this episode of the Optimal Body Podcast, physical therapists Doc Jen and Doctor Dom explore evidence-based strategies to reduce chronic pain sensitivity. They describe pain sensitivity as a "volume knob" in the nervous system that can be turned down through five key interventions: aerobic exercise, strength training, improved sleep, cognitive behavioral therapy, and graded exposure to feared movements. Each approach targets pain from physical and psychological angles. The hosts also highlight breathwork as a bonus tool for managing acute pain flares, encouraging listeners to combine these strategies for lasting relief.

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474 | What interventions have the best evidence for down-regulating pain sensitivity (breath, sleep, graded exposure, strength, walking)

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