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Hi, This Week in Medicine, we will be discussing First we will be discussing articles in New England Journal of MedicineExagamglogene Autotemcel for Severe Sickle Cell Disease Exagamglogene Autotemcel for Transfusion-Dependent β-Thalassemia Trial of Thrombectomy for Stroke with a Large Infarct of Unrestricted Size Journal of  American Medical AssociationPonatinib vs Imatinib in Frontline Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia Associations of Internal Medicine Residency Milestone Ratings and Certification Examination Scores With Patient OutcomesAnnals of Internal MedicineThe Safety of Outpatient Health Care: Review of Electronic Health Records Diagnostic Strategy Using Color Doppler Ultrasound of Temporal Arteries in Patients With High Clinical Suspicion of Giant Cell Arteritis: A Prospective Cohort StudyNature MedicineSingle-cell transcriptomic analyses reveal distinct immune cell contributions to epithelial barrier dysfunction in checkpoint inhibitor colitisLancetPreventive percutaneous coronary intervention versus optimal medical therapy alone for the treatment of vulnerable atherosclerotic coronary plaques (PREVENT): a multicentre, open-label, randomised controlled trialJournal of Clinical OncologyPhase II Trial of nab-Sirolimus in Patients With Advanced Malignant Perivascular Epithelioid Cell Tumors (AMPECT): Long-Term Efficacy and Safety Update journal of HepatologyClinical profiles and mortality rates are similar for metabolic dysfunction-associated steatotic liver disease and non-alcoholic fatty liver disease Molecular force-induced liberation of transforming growth factor-beta remodels the spleen for ectopic liver regenerationClinical Gastroenterology Type 1 Autoimmune Pancreatitis in Europe: Clinical Profile and Response to Treatment Screening for Fibrosis Promotes Lifestyle Changes: A Prospective Cohort Study in 4796 Individuals ENTERPRET: A Randomized Controlled Trial of Vedolizumab Dose Optimization in Patients With Ulcerative Colitis Who Have Early Nonresponse  Clinical Infectious DiseasesImpact of a Purified Microbiome Therapeutic on Abundance of Antimicrobial Resistance Genes in Patients With Recurrent Clostridioides difficile Infection A Systematic Review of Predictor Composition, Outcomes, Risk of Bias, and Validation of COVID-19 Prognostic Scores Compared Performance of the 2023 Duke–International Society for Cardiovascular Infectious Diseases, 2000 Modified Duke, and 2015 European Society of Cardiology Criteria for the Diagnosis of Infective Endocarditis in a French Multicenter Prospective Cohort Journal of Clinical Rheumatology Measurement of Neutrophil Extracellular Traps as a Biomarker for the Differential Diagnosis Between Antineutrophil Cytoplasmic Antibody–Positive Individuals With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis and Nonautoimmune Diseases Prediction of Treatment Effect of SLE-ITP Patients Based on Cost-Sensitive Neural Network and Variational Autoencoder  Arthritis and RheumatologyAnti-Inflammatory Effect of High-Density Lipoprotein Blunted by Delivery of Altered MicroRNA Cargo in Patients With Rheumatoid Arthritis American College of CardiologyLGE CMR and Sudden Death in Hypertrophic Cardiomyopathy  Journals of the American College of CardiologySacubitril/Valsartan-Related Hypotension in Patients With Heart Failure and Preserved or Mildly Reduced Ejection Fraction Journal of Clinical Endocrinology & MetabolismAssociation Between a History of Breast Cancer and Decreased Thyroid Cancer-specific MortalityNeurology:Association of Coffee Consumption and Prediagnostic Caffeine Metabolites With Incident Parkinson Disease in a Population-Based CohortChestSymptoms and Impaired Quality of Life After COVID-19 Hospitalization: Effect of Therapeutic Heparin in Non-ICU Patients in the Accelerating COVID-19 Therapeutic Interventions and Vaccines 4 Acute Trial Use and Outcomes of Peripheral Vasopressors in Early Sepsis-Induced Hypotension Across Michigan Hospitals  The American Journal of Respiratory and Critical Care Medicine Zinpentraxin Alfa for Idiopathic Pulmonary Fibrosis: The Randomized Phase III STARSCAPE Trial  Clinical Journal of American Society of NephrologyAssociations of Angiopoietin 2 and Vascular Endothelial Growth Factor-A Concentrations with Clinical End Points The Association of Intra-Abdominal Adhesions with Peritoneal Dialysis Catheter-Related ComplicationsKidney International reportsEarly Rituximab as an Add-On Therapy in Children With the Initial Episode of Nephrotic Syndrome Aversion to a High Salt Taste is Disturbed in Patients With CKD