5 19 2025

Hi, This Week in Medicine, we will be discussingNew England Journal of MedicineTolebrutinib in Nonrelapsing Secondary Progressive Multiple Sclerosis Tolebrutinib versus Teriflunomide in Relapsing Multiple Sclerosis Journal of  American Medical AssociationSpironolactone vs Amiloride for Resistant Hypertension  Annals of Internal MedicineMedical, Societal, and Ethical Considerations for Directed Blood Donation in 2025  British Medical JournalUse of gabapentinoid treatment and the risk of self-harm: population based self-controlled case series study LancetClinical presentation and epidemiological assessment of confirmed human mpox cases in DR Congo: a surveillance-based observational study  journal of HepatologyA new generation of non-invasive tests of liver fibrosis with improved accuracy in MASLD  Gastroenterology Physiological Data Collected From Wearable Devices Identify and Predict Inflammatory Bowel Disease Flares Clinical GastroenterologyReproducibility of the AGREE II Tool for Assessing the Methodological Quality of Clinical Practice Guidelines for the Management of Antithrombotic Agents in Patients Undergoing GI Endoscopy CirculationGenetic and Lifestyle Risks for Coronary Artery Disease and Long-Term Risk of Incident Dementia Subtypes Journals of the American College of CardiologyIschemia on Dobutamine Stress Echocardiography Predicts Efficacy of PCI: Results From the ORBITA-2 Trial JAMA CardiologyTrajectory of Cardiovascular Health Across Childhood and Adolescence Journal of Clinical Endocrinology & MetabolismRenal Protective Effect of Metformin in Type 2 Diabetes Patients Diabetes careEfficacy and Safety of Finerenone in Type 2 Diabetes: A Pooled Analysis of Trials of Heart Failure and Chronic Kidney Disease   NeurologyEndovascular Thrombectomy for Large Ischemic Core Stroke: A Systematic Review and Meta-Analysis of Randomized Controlled Trials  ChestEffect of Flow Rates of High-Flow Nasal Cannula on Extubation Outcomes The American Journal of Respiratory and Critical Care MedicineClinical and Biological Features of a Thickened Basement Membrane Zone in Asthma  Clinical Journal of American Society of NephrologyDialysis Dependence in Standard versus Accelerated Initiation of KRT in AKI: A Post Hoc Analysis Kidney International reportsScoping Review of Kidney Patients and Providers Perspectives on Disaster Management