EPISODE · Jun 3, 2026 · 6 MIN
5-Minute Summary: Does Preoperative Suzetrigine Impact ASC Opioid Consumption For Total Joint Arthroplasty?
from JOEI The Journal · host Ira H. Kirschenbaum, MD
Total knee arthroplasty (TKA) and total hip arthroplasty (THA) are some of the most commonly performed surgical procedures. Due to the soft tissue damage sustained intraoperatively, pain is a common occurrence which is frequently treated with opioid analgesics. Conventional wisdom still espouses large numbers of opioids for post-op pain relief. However, opioid related adverse events such as addiction, mental status changes, fall risk, and sedation remain a problem. Suzetrigine is a novel non-addictive FDA approved medication to treat acute pain. Lowering opioid use in the early phases of recovery has been shown to reduce long-term opioid use for patients.
What this episode covers
Total knee arthroplasty (TKA) and total hip arthroplasty (THA) are some of the most commonly performed surgical procedures. Due to the soft tissue damage sustained intraoperatively, pain is a common occurrence which is frequently treated with opioid analgesics. Conventional wisdom still espouses large numbers of opioids for post-op pain relief. However, opioid related adverse events such as addiction, mental status changes, fall risk, and sedation remain a problem. Suzetrigine is a novel non-addictive FDA approved medication to treat acute pain. Lowering opioid use in the early phases of recovery has been shown to reduce long-term opioid use for patients.
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5-Minute Summary: Does Preoperative Suzetrigine Impact ASC Opioid Consumption For Total Joint Arthroplasty?
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