EPISODE · May 22, 2025 · 10 MIN
52. 大象如何进化以击败癌症
from 知为谁 · host 知为谁
这些资料主要讨论了大象低癌症率这一反常现象，这一现象挑战了大型、长寿动物应该有更高癌症风险的预期，即Peto悖论。 研究发现，与人类只有一份p53肿瘤抑制基因不同，大象拥有多达20份该基因的变体，这些变体有助于阻止DNA受损细胞的繁殖。 有趣的是，有新的假说认为，大象体内如此多的p53基因最初可能是为了保护其暴露于高温环境的精子而进化出来的，而抵御癌症是其次要益处。 了解大象的这一独特机制，有望为人类癌症治疗提供新的靶点和思路。内容来源：https://newatlas.com/biology/elephants-beat-evolution-cancer-p53-gene-petos-paradox/
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52. 大象如何进化以击败癌症
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