EPISODE · Dec 8, 2025 · 15 MIN
526. 代糖破坏肠脑轴和奖励通路
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该来源是对一篇题为《干扰肠-脑轴：人工甜味剂如何重新连接微生物群和奖励通路》的科学评论的摘录，该评论发表在《国际分子科学杂志》上。这篇评论文章全面概述了非营养性甜味剂（NCSs）对人体生理的影响，特别是它们如何通过干扰肠道微生物群和改变大脑中的奖赏通路来破坏肠-脑轴。文章详细探讨了NCSs引发的微生物失调如何影响稳态进食（如饱腹感信号）和享乐性进食（如多巴胺奖励），认为NCSs通过将甜味与热量脱钩，可能导致对食物的过度渴望和代谢功能失调。它总结了动物和人类研究的证据，强调了NCSs对健康具有双重破坏作用，并呼吁进行更多综合性临床研究以制定缓解策略。内容来源：https://www.mdpi.com/1422-0067/26/20/10220
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526. 代糖破坏肠脑轴和奖励通路
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