EPISODE · Mar 3, 2026 · 27 MIN
582-癌症特征：疾病演进的逻辑框架与治疗蓝图
from 聊聊Sci
这篇由 Douglas Hanahan 撰写的综述论文是对癌症核心特征（Hallmarks of Cancer）理论的最新整合与升华。作者将二十五年来的研究成果提炼为四个互联的维度：一是癌症细胞通过突变获取的九项功能能力；二是辅助这些能力形成的五种赋能表型（如基因组不稳定和炎症）；三是肿瘤微环境中协同作恶的多种细胞类型；四是癌症与宿主在全身系统层面（如肥胖和老龄化）的复杂交互。文章强调，肿瘤并非简单的细胞集合，而是类似于一种“法外器官”，通过表型塑性和代谢重编程来适应环境并逃避治疗。最后，作者提出了一种基于机制的联合治疗策略，建议通过同时阻断多个核心特征来攻克单一疗法产生的耐药性问题。References: Hanahan D. Hallmarks of cancer—Then and now, and beyond[J]. Cell, 2026.前往小宇宙评论区与主播互动
Embed this episode
Ready to play
582-癌症特征：疾病演进的逻辑框架与治疗蓝图
0:00
27:11
1×
No transcript for this episode yet
Similar Episodes
No similar episodes found.
Similar Podcasts
Forfeiture Book Review: Ecocide and Sci-Fi
JP et al.
A whizz bang review of the complex themes in the new ecological Sci-Fi novel, FORFEITURE by JP Nebra
Deep Dream State
Neural Nets And Pretty Patterns
Deep Dream State is a full-cast dystopian sci-fi and desire horror audio drama by Neural Nets and Pretty Patterns. As the originating work of desire horror, it locates the uncanny inside wanting itself. While conventional horror positions you against a threat, desire horror implicates you in it. The horror emerges from recognition: the realization of why characters stay, and why surrender feels like relief. Since 2017, the show has used research in dream science, surveillance studies, behavioral economics, and advertising technology to examine systems of control through immersive sound design and full-cast performance.
Frequently Asked Questions
How long is this episode of 聊聊Sci?
This episode is 27 minutes long.
When was this 聊聊Sci episode published?
This episode was published on March 3, 2026.
Can I download this 聊聊Sci episode?
Yes. Use the download control on the episode player to save the publisher-provided media file.
URL copied to clipboard!