EPISODE · Dec 13, 2025 · 55 MIN
#595: The Estrobolome Explained: How Your Gut Shapes Your Hormones
from Vitality Radio Podcast with Jared St. Clair · host Jared St. Clair
On this episode of Vitality Radio, Jared welcomes functional medicine dietitian and gut-health expert Lisa Smith for a deep dive into one of the most overlooked systems influencing hormone balance: the estrobolome. If you’ve never heard that word before, you’re not alone — but by the end of this conversation you’ll understand why the estrobolome may be the missing link in stubborn hormone symptoms, estrogen dominance, thyroid sluggishness, mood changes, and even men’s testosterone challenges. Jared and Lisa break down how gut bacteria influence estrogen detoxification, what beta-glucuronidase is actually doing behind the scenes, why bile flow matters (especially if you don’t have a gallbladder), and how fiber, cruciferous vegetables, and targeted nutrients can support healthy hormone metabolism. This is a practical, empowering discussion designed to help you understand root causes rather than chase symptoms. Whether you’re navigating perimenopause, PCOS, thyroid issues, mood swings, stubborn weight, or low energy, this episode brings science down to earth with simple, realistic starting points for rebuilding gut balance and restoring hormonal resiliency — naturally and safely.Products:Precision ProbioticLiverVitality EndoCleanseAdditional Information:Pretty Well PodcastInstagramLisa Smith WellnessVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.
What this episode covers
On this episode of Vitality Radio, Jared welcomes functional medicine dietitian and gut-health expert Lisa Smith for a deep dive into one of the most overlooked systems influencing hormone balance: the estrobolome. If you’ve never heard that word before, you’re not alone — but by the end of this conversation you’ll understand why the estrobolome may be the missing link in stubborn hormone symptoms, estrogen dominance, thyroid sluggishness, mood changes, and even men’s testosterone challenges. Jared and Lisa break down how gut bacteria influence estrogen detoxification, what beta-glucuronidase is actually doing behind the scenes, why bile flow matters (especially if you don’t have a gallbladder), and how fiber, cruciferous vegetables, and targeted nutrients can support healthy hormone metabolism. This is a practical, empowering discussion designed to help you understand root causes rather than chase symptoms. Whether you’re navigating perimenopause, PCOS, thyroid issues, mood swings, stubborn weight, or low energy, this episode brings science down to earth with simple, realistic starting points for rebuilding gut balance and restoring hormonal resiliency — naturally and safely.Products:Precision ProbioticLiverVitality EndoCleanseAdditional Information:Pretty Well PodcastInstagramLisa Smith WellnessVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.
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#595: The Estrobolome Explained: How Your Gut Shapes Your Hormones
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