6 3 2024

Hi, This Week in Medicine, we will be discussing New England Journal of MedicineAficamten for Symptomatic Obstructive Hypertrophic Cardiomyopathy Intensive Ambulance-Delivered Blood-Pressure Reduction in Hyperacute Stroke Journal of  American Medical AssociationAspirin vs Placebo as Adjuvant Therapy for Breast CancerThe Alliance A011502 Randomized Trial Smoking Cessation After Initial Treatment Failure With Varenicline or Nicotine ReplacementA Randomized Clinical Trial Annals of Internal Medicine Efficacy of Voluntary Medical Male Circumcision to Prevent HIV Infection Among Men Who Have Sex With Men Benefits and Risks Associated With Statin Therapy for Primary Prevention in Old and Very Old Adults  British Medical JournalTislelizumab plus chemotherapy versus placebo plus chemotherapy as first line treatment for advanced gastric or gastro-oesophageal junction adenocarcinoma Epidural analgesia during labour and severe maternal morbidity  Journal of Clinical OncologyImpact of Helicobacter pylori Infection and Treatment on Colorectal Cancer in a Large, Nationwide Cohort journal of HepatologyPrimary hypocholesterolemia is associated with an increased risk of hepatic complications in the general population Clinical Gastroenterology  Validated Clinical Score to Predict Gastroesophageal Reflux in Patients With Chronic Laryngeal Symptoms: COuGH RefluX Hypercholesterolemia Is Associated With Dysregulation of Lipid Metabolism and Poor Prognosis in Primary Biliary Cholangitis  Journal of Clinical Rheumatology Choroidal Thickness Is a Biomarker Associated With Response to Treatment in Ankylosing Spondylitis  Arthritis and RheumatologyEffect of Recent Antirheumatic Drug on Features of Rheumatoid Arthritis–Associated Lymphoproliferative Disorders CirculationComparison of Incidence and Prognostic Impact of Ischemic, Major Bleeding and Heart Failure Events in Patients With Chronic Coronary Syndrome: Insights From the CORONOR Registry American College of Cardiology Coronary Atherosclerotic Plaque Activity and Risk of MI  Journal of Clinical Endocrinology & MetabolismInsufficient Bone Mineralization to Sustain Mechanical Load of Weight in Obese Boys: A Cross-Sectional Study  Neurology:Distribution of Silent Cerebral Infarcts in Adults With Sickle Cell Disease  ChestTolerability Outcomes of American Thoracic Society/Infectious Diseases Society of America Guideline-Recommended Multidrug Antibiotic Treatment for Mycobacterium avium Complex Pulmonary Disease in US Medicare Beneficiaries With Bronchiectasis Prophylactic Minocycline for Delirium in Critically Ill Patients Clinical Journal of American Society of NephrologySotagliflozin and Kidney Outcomes, Kidney Function, and Albuminuria in Type 2 Diabetes and CKD: A Secondary Analysis of the SCORED Trial  Kidney International reportsPregnancy and Family Planning in Women With Kidney Disease