622-大脑同构:皮层、小脑与海马体的功能连接梯度研究 episode artwork

EPISODE · Mar 11, 2026 · 26 MIN

622-大脑同构:皮层、小脑与海马体的功能连接梯度研究

from 聊聊Sci

这项研究利用梯度映射技术和静息态功能磁共振成像,系统揭示了人类大脑皮层、小脑与海马体之间功能连接梯度的对应关系。研究人员在两个大规模数据集(人数超过2000人)中发现,这三个结构共用两套主要的功能组织原则,即关联-感觉运动梯度和表征-调节梯度。这些发现表明,不同脑区的功能协调可以统一在基于预测处理的计算框架下,用于解释大脑如何维持机体稳态。该成果为理解脑网络宏观组织提供了一个整合性视角,有助于深入探索认知与行为的神经机制。研究还证实了这些连接模式在个体水平上具有高度的可复制性,对研究精神和神经退行性疾病具有潜在意义。References: Katsumi Y, Zhang J, Chen D, et al. Correspondence of functional connectivity gradients across human isocortex, cerebellum, and hippocampus[J]. Communications Biology, 2023, 6(1): 401.前往小宇宙评论区与主播互动

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622-大脑同构:皮层、小脑与海马体的功能连接梯度研究

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