669-嗅神经母细胞瘤单细胞转录组图谱与亚型分类研究

这项发表在《Nature Cancer》的研究通过单细胞转录组测序技术，深入解析了嗅神经母细胞瘤（ONB）的细胞图谱。研究者不仅揭示了肿瘤内部的高度异质性，还突破性地提出了由神经型、基底型和间质型组成的三分类系统。通过对比正常嗅上皮细胞，研究确立了不同肿瘤亚型的细胞起源，并发现了与恶性转化相关的关键分子特征。此外，该研究识别出的特定生物标志物可用于临床预后评估，并为精准化疗和免疫治疗提供了新的策略建议。References: Yang J, Song X, Zhang H, et al. Single-cell transcriptomic landscape deciphers olfactory neuroblastoma subtypes and intra-tumoral heterogeneity[J]. Nature Cancer, 2024, 5(12): 1919-1939.前往小宇宙评论区与主播互动

Episode metadata supplied by the publisher feed · Published Mar 20, 2026

Embed this episode

Attribution link and audio player

NOW PLAYING

669-嗅神经母细胞瘤单细胞转录组图谱与亚型分类研究

0:00 20:10

1×

No transcript for this episode yet

We transcribe on demand. Request one and we'll notify you when it's ready — usually under 10 minutes.

Share this episode

Similar Episodes

No similar episodes found.

Similar Podcasts

Forfeiture Book Review: Ecocide and Sci-Fi JP et al. A whizz bang review of the complex themes in the new ecological Sci-Fi novel, FORFEITURE by JP Nebra

Frequently Asked Questions

How long is this episode of 聊聊Sci?

This episode is 20 minutes long.

When was this 聊聊Sci episode published?

This episode was published on March 20, 2026.

Can I download this 聊聊Sci episode?

Yes. Use the download control on the episode player to save the publisher-provided media file.

URL copied to clipboard!