7 14 2025

Hi, This Week in Medicine, we will be discussing

 New England Journal of Medicine

 As-Needed Albuterol–Budesonide in Mild Asthma

Global Effect of Cardiovascular Risk Factors on Lifetime Estimates

Intravenous Tenecteplase before Thrombectomy in Stroke

Overall Survival with Inavolisib in PIK3CA-Mutated Advanced Breast Cancer

Journal of  American Medical Association

Obesity Variation Among Asian, Native Hawaiian or Pacific Islander Adults in the US

Annals of Internal Medicine

Development and Validation of Body Mass Index–Specific Waist Circumference Thresholds in Postmenopausal Women

 British Medical Journal

Global, regional, and national characteristics of the main causes of increased disease burden due to the covid-19 pandemic

 Lancet

Mitapivat in adults with non-transfusion-dependent α-thalassaemia or β-thalassaemia (ENERGIZE): a phase 3, international, randomised, double-blind, placebo-controlled trial

  JAMA oncology 

Adjuvant Chemoradiation and Immunotherapy for Extrahepatic Cholangiocarcinoma and Gallbladder CancerA Randomized Clinical Trial

 Journal of Clinical Oncology

Use of Low-Value Cancer Treatments in Medicare Advantage Versus Traditional Medicare

journal of Hepatology

Modeling the health and economic impact of pharmacologic therapies for MASLD in the United States

  Gastroenterology

Diagnostic Accuracy of Timed Barium Esophagram for Achalasia

  Clinical Gastroenterology

 Lymphocytic Esophagitis: A Histologic Pattern of Various Underlying Disorders

  Rheumatology 

Association of Soluble Immune Checkpoint Molecules PD1 and 4-1BB With CTLA-4Ig Treatment Response in Early Rheumatoid Arthritis

 Circulation

 Burden of Cardiovascular Outcomes After SARS-CoV-2 Infection in South Korea and Japan: A Binational Population-Based Cohort Study

 Journals of the American College of Cardiology

Plaque Vulnerability and Cardiovascular Risk Factor Burden in Acute Coronary Syndrome: An Optical Coherence Tomography Analysis

  JAMA Cardiology

Cumulative Life’s Essential 8 Scores and Cardiovascular Disease Risk

 Journal of Clinical Endocrinology & Metabolism

Effects of a Carbohydrate-Restricted Diet on β-Cell Response in Adults With Type 2 Diabetes

 Diabetes care

Economic Costs Attributed to Diagnosed Diabetes in Each U.S. State and the District of Columbia: 2021

 Neurology

Neighborhood Socioeconomic Status and the Functional Outcome of Patients Treated With Endovascular Thrombectomy for Ischemic Stroke

  Chest

Prolonged Mechanical Ventilation in Critically Ill Patients

 he American Journal of Respiratory and Critical Care Medicine

Prevention of Cardiovascular and Other Systemic Adverse Outcomes in Patients with Asthma Treated with Biologics

Clinical Journal of American Society of Nephrology

High Heat Exposure and Medical Utilization among the CKD Population

Kidney International reports

Holistic Impact of CKD: A Clinical, Economic, and Environmental Analysis by IMPACT CKD