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Hi, This Week in Medicine, we will be discussingNew England Journal of MedicineTenecteplase for Ischemic Stroke at 4.5 to 24 Hours without Thrombectomy Risankizumab versus Ustekinumab for Moderate-to-Severe Crohn’s DiseaseOral Nirmatrelvir–Ritonavir as Postexposure Prophylaxis for Covid-19 Journal of  American Medical AssociationElectroencephalography-Guided Anesthesia and Delirium in Older Adults After Cardiac SurgeryThe ENGAGES-Canada Randomized Clinical Trial Annals of Internal Medicine Comparative Effectiveness and Safety of Apixaban, Rivaroxaban, and Warfarin in Patients With Cirrhosis and Atrial Fibrillation: A Nationwide Cohort StudyBritish Medical JournalLee Silverman voice treatment versus NHS speech and language therapy versus control for dysarthria in people with Parkinson’s disease (PD COMM): pragmatic, UK based, multicentre, three arm, parallel group, unblinded, randomised controlled trial  LancetLong-term colchicine for the prevention of vascular recurrent events in non-cardioembolic stroke (CONVINCE): a randomised controlled trial Post-trial monitoring of a randomised controlled trial of intensive glycaemic control in type 2 diabetes extended from 10 years to 24 years (UKPDS 91) Hemato Oncology.Journal of Clinical OncologyMethylphenidate Versus Placebo for Treating Fatigue in Patients With Advanced Cancer: Randomized, Double-Blind, Multicenter, Placebo-Controlled Trial Phase Ib Study of Unesbulin (PTC596) Plus Dacarbazine for the Treatment of Locally Recurrent, Unresectable or Metastatic, Relapsed or Refractory Leiomyosarcoma journal of HepatologyUsing liver stiffness to predict and monitor the risk of decompensation and mortality in patients with alcohol-related liver diseaseGastroenterologyClinical Gastroenterology Validation of the Laryngeal Cognitive-Affective Tool Outcomes of High-Grade Immune Checkpoint Inhibitor Hepatitis in Hospitalized and Nonhospitalized Patients Being Breastfed in Infancy and Risk of Colorectal Cancer and Precursor Lesions Infectious Diseases Clinical Infectious DiseasesDevelopment of Patient Safety Measures to Identify Inappropriate Diagnosis of Common Infections  Central Nervous System Antimicrobial Exposure and Proposed Dosing for Anthrax Meningitis Rheumatology   Journal of Clinical Rheumatology Choroidal Thickness Is a Biomarker Associated With Response to Treatment in Ankylosing Spondylitis Arthritis and RheumatologyUsing Two Predictive Models to Capture Two Types of Poor Outcomes in Knee Arthroplasty: A Multisite Longitudinal Cohort Study  Cardiology   Journals of the American College of CardiologyEffects of Rapid Uptitration of Neurohormonal Blockade on Effective,  OCT-Guided vs Angiography-Guided Coronary Stent Implantation in Complex Lesions: An ILUMIEN IV Substudy  EndocrinologyHere are the  articles   from Journal of Clinical Endocrinology & MetabolismEffects of Exogenous GIP and GLP-2 on Bone Turnover in Individuals With Type 2 Diabetes  NeurologyHere are the  articles   from  NeurologyPrevalence of Suicidality in Adolescents With Newly Diagnosed Focal Epilepsy at Diagnosis and Over the Following 36 Months Next we will be discussing articles In the field of Pulmonary and Critical care ChestInternational Variation in Severe Exacerbation Rates in Patients With Severe Asthma Clinician- and Patient-Identified Solutions to Reduce the Fragmentation of Post-ICU Care in Australia  The American Journal of Respiratory and Critical Care MedicineThe Role of Neighborhood Air Pollution in Disparate Racial and Ethnic Asthma Acute Care Use Predicting Obstructive Sleep Apnea Based on Computed Tomography Scans Using Deep Learning Models Next we will be discussing articles In the field of NephrologyClinical Journal of American Society of NephrologyAcute Kidney Injury, Systemic Inflammation, and Long-Term Cognitive Function: ASSESS-AKI Kidney International reportsEffects of Once-Weekly Semaglutide on Kidney Disease Outcomes by KDIGO Risk Category in the SUSTAIN 6 Trial Efficacy and Safety of Lumasiran in Patients With Primary Hyperoxaluria Type 1: Results from a Phase III Clinical Trial Prospective Study of Change in Skin Autofluorescence Over Time and Mortality in People Receiving Hemodialysis Etelcalcetide use During Maintenance Hemodialysis and Incidence of Parathyroidectomy After Kidney Transplantation