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Hi, This Week in Medicine, we will be discussing

New England Journal of Medicine

Tenecteplase for Ischemic Stroke at 4.5 to 24 Hours without Thrombectomy

Risankizumab versus Ustekinumab for Moderate-to-Severe Crohn’s Disease

Oral Nirmatrelvir–Ritonavir as Postexposure Prophylaxis for Covid-19

Journal of  American Medical Association

Electroencephalography-Guided Anesthesia and Delirium in Older Adults After Cardiac SurgeryThe ENGAGES-Canada Randomized Clinical Trial

Annals of Internal Medicine

Comparative Effectiveness and Safety of Apixaban, Rivaroxaban, and Warfarin in Patients With Cirrhosis and Atrial Fibrillation: A Nationwide Cohort Study

British Medical Journal

Lee Silverman voice treatment versus NHS speech and language therapy versus control for dysarthria in people with Parkinson’s disease (PD COMM): pragmatic, UK based, multicentre, three arm, parallel group, unblinded, randomised controlled trial

 Lancet

Long-term colchicine for the prevention of vascular recurrent events in non-cardioembolic stroke (CONVINCE): a randomised controlled trial

Post-trial monitoring of a randomised controlled trial of intensive glycaemic control in type 2 diabetes extended from 10 years to 24 years (UKPDS 91)

Hemato Oncology.

Journal of Clinical Oncology

Methylphenidate Versus Placebo for Treating Fatigue in Patients With Advanced Cancer: Randomized, Double-Blind, Multicenter, Placebo-Controlled Trial

Phase Ib Study of Unesbulin (PTC596) Plus Dacarbazine for the Treatment of Locally Recurrent, Unresectable or Metastatic, Relapsed or Refractory Leiomyosarcoma

journal of Hepatology

Using liver stiffness to predict and monitor the risk of decompensation and mortality in patients with alcohol-related liver disease

Gastroenterology

Clinical Gastroenterology

 Validation of the Laryngeal Cognitive-Affective Tool

Outcomes of High-Grade Immune Checkpoint Inhibitor Hepatitis in Hospitalized and Nonhospitalized Patients

Being Breastfed in Infancy and Risk of Colorectal Cancer and Precursor Lesions

Infectious Diseases

 Clinical Infectious Diseases

Development of Patient Safety Measures to Identify Inappropriate Diagnosis of Common Infections 

Central Nervous System Antimicrobial Exposure and Proposed Dosing for Anthrax Meningitis

Rheumatology 

  Journal of Clinical Rheumatology 

Choroidal Thickness Is a Biomarker Associated With Response to Treatment in Ankylosing Spondylitis

Arthritis and Rheumatology

Using Two Predictive Models to Capture Two Types of Poor Outcomes in Knee Arthroplasty: A Multisite Longitudinal Cohort Study

 Cardiology

 Journals of the American College of Cardiology

Effects of Rapid Uptitration of Neurohormonal Blockade on Effective,  

OCT-Guided vs Angiography-Guided Coronary Stent Implantation in Complex Lesions: An ILUMIEN IV Substudy

Endocrinology

Here are the  articles   from Journal of Clinical Endocrinology & Metabolism

Effects of Exogenous GIP and GLP-2 on Bone Turnover in Individuals With Type 2 Diabetes 

Neurology

Here are the  articles   from  Neurology

Prevalence of Suicidality in Adolescents With Newly Diagnosed Focal Epilepsy at Diagnosis and Over the Following 36 Months

Next we will be discussing articles In the field of Pulmonary and Critical care

 Chest

International Variation in Severe Exacerbation Rates in Patients With Severe Asthma

Clinician- and Patient-Identified Solutions to Reduce the Fragmentation of Post-ICU Care in Australia

 The American Journal of Respiratory and Critical Care Medicine

The Role of Neighborhood Air Pollution in Disparate Racial and Ethnic Asthma Acute Care Use

Predicting Obstructive Sleep Apnea Based on Computed Tomography Scans Using Deep Learning Models

Next we will be discussing articles In the field of Nephrology

Clinical Journal of American Society of Nephrology

Acute Kidney Injury, Systemic Inflammation, and Long-Term Cognitive Function: ASSESS-AKI

Kidney International reports

Effects of Once-Weekly Semaglutide on Kidney Disease Outcomes by KDIGO Risk Category in the SUSTAIN 6 Trial

Efficacy and Safety of Lumasiran in Patients With Primary Hyperoxaluria Type 1: Results from a Phase III Clinical Trial

Prospective Study of Change in Skin Autofluorescence Over Time and Mortality in People Receiving Hemodialysis

Etelcalcetide use During Maintenance Hemodialysis and Incidence of Parathyroidectomy After Kidney Transplantation