7 28 2025

Hi, This Week in Medicine, we will be discussingFirst we will be discussing articles in New England Journal of Medicine Weekly Fixed-Dose Insulin Efsitora in Type 2 Diabetes without Previous Insulin Therapy Trastuzumab Deruxtecan or Ramucirumab plus Paclitaxel in Gastric Cancer Tarlatamab in Small-Cell Lung Cancer after Platinum-Based Chemotherapy Ivermectin to Control Malaria — A Cluster-Randomized Trial Journal of  American Medical AssociationTelehealth and Online Cognitive Behavioral Therapy for Chronic Pain Annals of Internal MedicineGlucagon-Like Peptide-1 Receptor Agonists and Incidence of Dementia Among Older Adults With Type 2 Diabetes   British Medical JournalGlobal, regional, and national characteristics of the main causes of increased disease burden due to the covid-19 pandemic   JAMA oncology Nivolumab and Ipilimumab Combination Treatment in Advanced Ovarian and Endometrial Clear Cell CancersA Nonrandomized Clinical Trial  journal of HepatologyAll-cause and cause-specific mortality in patients with chronic hepatitis B and concurrent steatotic liver disease GastroenterologyCapsule Endoscopy–Guided Proactive Treat-to-Target Versus Continued Standard Care in Patients With Quiescent Crohn’s Disease: A Randomized Controlled Trial Clinical Gastroenterology Real-world Clinical Effectiveness and Safety of Vedolizumab and Adalimumab in Biologic-naive Patients With Crohn’s Disease: Results From the EVOLVE Study  CirculationEfficacy and Safety of Inclisiran in Adolescents With Genetically Confirmed Homozygous Familial Hypercholesterolemia: Results From the Double-Blind, Placebo-Controlled Part of the ORION-13 Randomized Trial  Journals of the American College of CardiologyBiolimus-Eluting Biomatrix Stent vs a Dual-Therapy Sirolimus-Eluting Stent in PCI: The SORT OUT XI Randomized Trial JAMA CardiologyOCT vs Angiography for Guidance of Percutaneous Coronary Intervention of Calcified LesionsThe CALIPSO Randomized Clinical Trial  Journal of Clinical Endocrinology & MetabolismThe Role of Whole Food Plant-Based Food Intake on Postprandial Glycemia in Type 1 Diabetes Diabetes careAssociations of Concurrent Hypertension and Type 2 Diabetes With Mortality Outcomes: A Prospective Study of U.S. Adults  ChestClinical Remission Over 2 Years With Benralizumab in Severe Eosinophilic Asthma The American Journal of Respiratory and Critical Care MedicineDeep Learning Estimation of Small Airway Disease from Inspiratory Chest Computed Tomography: Clinical Validation, Repeatability, and Associations with Adverse Clinical Outcomes in Chronic Obstructive Pulmonary Disease  Clinical Journal of American Society of NephrologyUnveiling the Causal Relationship between Thyroid and Kidney Function: A Multivariable Mendelian Randomization Here are the  articles   from Kidney International reportsCharacterization of Monogenic Kidney Disease in Older Patients With CKD