7 7 2025

Hi, This Week in Medicine, we will be discussing

 New England Journal of Medicine

Structured Exercise after Adjuvant Chemotherapy for Colon Cancer

Tirzepatide as Compared with Semaglutide for the Treatment of Obesity

Neoadjuvant and Adjuvant Pembrolizumab in Locally Advanced Head and Neck Cancer

  Journal of  American Medical Association

Lorundrostat in Participants With Uncontrolled Hypertension and Treatment-Resistant Hypertension: The Launch-HTN Randomized Clinical Trial

 Annals of Internal Medicine

Risk for Stroke After Newly Diagnosed Atrial Fibrillation During Hospitalization for Other Primary Diagnoses

A Retrospective Cohort Study

  British Medical Journal

Global, regional, and national characteristics of the main causes of increased disease burden due to the covid-19 pandemic

  Lancet

Surgery versus corticosteroid injection for carpal tunnel syndrome (DISTRICTS): an open-label, multicentre, randomised controlled trial

  Gastroenterology

Noncontrast Magnetic Resonance Imaging vs Ultrasonography for Hepatocellular Carcinoma Surveillance: A Randomized, Single-Center Trial

  Clinical Gastroenterology

 Esophageal Expert Development of a Preliminary Question Prompt List for Adults With Eosinophilic Esophagitis: A Modified Delphi Study

  Clinical Infectious Diseases

Glucocorticoid Dosing and Implications for Vaccination: Evolution of Global Definitions

 Journal of Clinical Rheumatology 

Association of Klotho and Gout in Middle-Aged and Older Adults: National Health and Nutrition Survey (2007–2016)

  Circulation

FMO2 Prevents Pathological Cardiac Hypertrophy by Maintaining the ER-Mitochondria Association Through Interaction With IP3R2-Grp75-VDAC1

  Journals of the American College of Cardiology

Long-Acting Factor XI Inhibition and Periprocedural Bleeding: An Analysis From AZALEA-TIMI 71

  JAMA Cardiology

Cardiomyopathy-Associated Gene Variants in Atrial Fibrillation

 Journal of Clinical Endocrinology & Metabolism

Cost-effectiveness Analysis Comparing Conventional and Digital Software Supported Management for Hypothyroidism

 Diabetes care

Impact of Islet Transplantation on Diabetes Complications and Mortality in Patients Living With Type 1 Diabetes

 Neurology

Association of Predicted Visceral Fat Percentage With Dementia Risk in Older Adults: The Role of Genetic Risk and Lifestyle

 Chest

Ventilator-Associated Pneumonia in Low- and Middle-Income vs High-Income Countries

 The American Journal of Respiratory and Critical Care Medicine

Early versus Delayed Switching from Controlled to Assisted Ventilation: A Target Trial Emulation

 Clinical Journal of American Society of Nephrology

High Heat Exposure and Medical Utilization among the CKD Population

 Kidney International reports

Effect of Sleep Characteristics on Rapid Estimated GFR Decline in Adults with Normal Kidney Function