703-植物无限生长:LFY与TFL1的负反馈调控机制 episode artwork

EPISODE · Mar 27, 2026 · 26 MIN

703-植物无限生长:LFY与TFL1的负反馈调控机制

from 聊聊Sci

这项研究通过结合实验数据与计算机模拟,揭示了植物顶端分生组织维持无限生长(不确定性)的分子机制。研究发现,在拟南芥进入生殖生长阶段时,两种关键因子 LFY 和 TFL1 之间形成了一个负反馈调节环。在这个机制中,促进花发育的因子 LFY 会激活其竞争对手 TFL1 的表达,而 TFL1 随后反过来限制 LFY 的过量积累,从而缓冲了环境信号对顶端分生组织的冲击。这种调节作用通过抵消成花素(FT)带来的强烈诱导信号,确保植物在持续产生花朵的同时,主茎尖端仍能保留干细胞 pool 以实现长期发育。相比之下,侧向分生组织因缺乏这种反馈缓冲机制而转化为确定的花朵结构。该成果解释了相邻细胞群如何对同一环境指令产生截然不同的发育响应,为优化作物株型和提高粮食安全提供了重要理论依据。References: Huang T, Hodgens C, Prakash S, et al. A negative feedback loop between TERMINAL FLOWER1 and LEAFY protects inflorescence indeterminacy[J]. Science, 2026: eadv5429.前往小宇宙评论区与主播互动

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703-植物无限生长:LFY与TFL1的负反馈调控机制

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