EPISODE · Mar 29, 2026 · 23 MIN
712-肠道菌群：老化与认知衰退的纽带
from 聊聊Sci
这份研究报告揭示了肠道微生物群的变化如何通过影响肠脑轴来导致老年阶段的认知能力下降。科学家发现，随着年龄增长，一种名为 P. goldsteinii 的细菌比例增加，它会释放中链脂肪酸。这些分子会激活免疫细胞并引发炎症反应，进而抑制连接大脑与身体关键器官的迷走神经。这种信号传导受阻最终会导致大脑海马体活动减弱，从而损害动物的学习与记忆功能。虽然该实验主要在小鼠身上进行，但研究结果为未来通过饮食干预或微生物疗法来治疗人类认知障碍提供了重要思路。References: Cheng Y T, Mazmanian S K. Gut microbes affect cognition during ageing[J]. 2026.前往小宇宙评论区与主播互动
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712-肠道菌群：老化与认知衰退的纽带
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