8 11 2025

Hi, This Week in Medicine, we will be discussing First we will be discussing articles in New England Journal of Medicine Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes Ciprofloxacin versus Aminoglycoside–Ciprofloxacin for Bubonic Plague Vepdegestrant, a PROTAC Estrogen Receptor Degrader, in Advanced Breast Cancer First-Line Camizestrant for Emerging ESR1-Mutated Advanced Breast Cancer Journal of  American Medical AssociationAlteplase for Acute Ischemic Stroke at 4.5 to 24 Hours  Annals of Internal MedicineEfficacy of a Very-Low-Calorie Weight Loss Diet Plus Exercise Compared With Exercise Alone on Hip Osteoarthritis Pain: A Randomized Controlled Trial  JAMA oncology Modeling Population-Level Impacts of Cell-Free DNA Screening for Colorectal Cancer in Canada  Journal of Clinical OncologyRandomized Phase II Study of Concurrent Versus Sequential Pembrolizumab in Combination With Chemoradiation in Locally Advanced Head and Neck Cancer journal of HepatologyA phase IIb randomised-controlled trial of the FFAR1/FFAR4 agonist icosabutate in MASH   GastroenterologyRisk of Gastric Adenocarcinoma After Eradication of Helicobacter pylori Clinical Gastroenterology Lymphocytic Esophagitis: A Histologic Pattern of Various Underlying Disorders Clinical Infectious DiseasesTarget Trial Emulation of SARS-CoV-2 Infection Versus No Infection and Risk of Post–COVID-19 Conditions in the Omicron Variant Versus Prior Eras  Rheumatology Peripheral Biomarker Signatures in Rheumatoid Arthritis–Associated Interstitial Lung Disease  CirculationAbelacimab Versus Rivaroxaban in Patients With Atrial Fibrillation on Antiplatelet Therapy: A Prespecified Analysis of the AZALEA-TIMI 71 Trial  Journals of the American College of CardiologyUsing Compression Stockings to Prevent Recurrence of Vasovagal Syncope: A Randomized Sham-Controlled Trial JAMA CardiologyCumulative Life’s Essential 8 Scores and Cardiovascular Disease Risk  Journal of Clinical Endocrinology & MetabolismTrends in Osteoporosis Drug Therapy Receipt Among Commercial and Medicare Advantage Enrollees in the United States, 2011-2022 Diabetes careLack of Validity of the Glucose Management Indicator in Type 1 Diabetes in Pregnancy  NeurologyStatin Initiation and Dementia Incidence in a Large Health Care System From 1997 to 2020: A Target Trial Emulation Study  The American Journal of Respiratory and Critical Care MedicineEndotypes of Pseudomonas aeruginosa Infection in Bronchiectasis Are Associated with Inhaled Antibiotic Response: Results from Two Randomized, Double-Blind, Placebo-controlled Phase III Trials (ORBIT 3 and ORBIT 4) Clinical Journal of American Society of NephrologySodium-Glucose Cotransporter-2 Inhibitor Therapy and Longitudinal Changes in Kidney Function among Veterans with Autosomal Dominant Polycystic Kidney Disease Here are the  articles   from Kidney International reportsA Systematic Review of Treatment for Acute Interstitial Nephritis