8 18 2025

Hi, This Week in Medicine, we will be discussing

New England Journal of Medicine

Coadministered Cagrilintide and Semaglutide in Adults with Overweight or Obesity

Cagrilintide–Semaglutide in Adults with Overweight or Obesity and Type 2 Diabetes

A Crossover Trial of Hospital-Wide Lactated Ringer’s Solution versus Normal Saline

  Journal of  American Medical Association

 Dalbavancin for Treatment of Staphylococcus aureus Bacteremia

 Annals of Internal Medicine

Geographic Variation in Receipt of Care by Specialized Oncologists

 British Medical Journal

Global, regional, and national characteristics of the main causes of increased disease burden due to the covid-19 pandemic

  Lancet

Extending the duration of endocrine treatment for early breast cancer: patient-level meta-analysis of 12 randomised trials of aromatase inhibitors in 22 031 postmenopausal women already treated with at least 5 years of endocrine therapy

 JAMA oncology 

Integrating Quality of Life and Survival in Systemic Therapy for Advanced Hepatocellular CarcinomaA Network Meta-Analysis

  Clinical Gastroenterology

Noninvasive Disease Assessment in Eosinophilic Esophagitis With Fractionated Exhaled Nitric Oxide, Blood, and Fecal Biomarkers

  Clinical Infectious Diseases

  Journal of Clinical Rheumatology 

Validation of the ANCA-Associated Vasculitis Patient-Reported Outcomes Questionnaire in a Latin American Vasculitis Cohort

  Circulation

Association of Smoking Cannabis With Cardiovascular Events Among Veterans With Coronary Artery Disease

 Journals of the American College of Cardiology

Recurrent Events Analysis of MASTER DAPT: Total Ischemic and Bleeding Events After Abbreviated vs Prolonged DAPT in HBR Patients

  JAMA Cardiology

Early Childhood Food Insecurity and Cardiovascular Health in Young Adulthood

  Journal of Clinical Endocrinology & Metabolism

Trends in Osteoporosis Drug Therapy Receipt Among Commercial and Medicare Advantage Enrollees in the United States, 2011-2022

 Diabetes care

Lack of Validity of the Glucose Management Indicator in Type 1 Diabetes in Pregnancy 

 Neurology

Real-World Evidence of Brexpiprazole Use and 6-Month Mortality, Hospitalization, and Emergency Department Visits Among Persons With Dementia

 Chest

Continuous Glucose Monitoring for Hyperglycemia in Critically Ill Patients

A Randomized Controlled Trial

 The American Journal of Respiratory and Critical Care Medicine

Endotypes of Pseudomonas aeruginosa Infection in Bronchiectasis Are Associated with Inhaled Antibiotic Response: Results from Two Randomized, Double-Blind, Placebo-controlled Phase III Trials (ORBIT 3 and ORBIT 4)

 Clinical Journal of American Society of Nephrology

Core Outcome Measure for Life Participation in Patients with CKD: Standardized Outcomes in Nephrology Workshops Report

Frailty in Adults with CKD and Validation of the Kidney Failure Risk Equation in Frailty Subgroups

 Kidney International reports

A Systematic Review of Treatment for Acute Interstitial Nephritis

Double-Icodextrin Dose Randomized Controlled Trial of a Double Icodextrin Dose for Older Patients on Incremental Continuous Ambulatory Peritoneal Dialysis