8 4 2025

Hi, This Week in Medicine, we will be discussing

 New England Journal of Medicine

Measurable Residual Disease–Guided Therapy in Newly Diagnosed Myeloma

A Randomized Trial of Acute Normovolemic Hemodilution in Cardiac Surgery

 Journal of  American Medical Association

Impact of the MISSION Act on Quality and Outcomes of Major Cardiovascular Procedures in Veterans

 Annals of Internal Medicine

Social Determinants of Health and Long COVID

  British Medical Journal

Sex related differences in efficacy and safety of antithrombotic therapy in patients with coronary artery disease

  Lancet

Adjuvant chemotherapy and hormonotherapy versus adjuvant hormonotherapy alone for women aged 70 years and older with high-risk breast cancer based on the genomic grade index (ASTER 70s): a randomised phase 3 trial

 JAMA oncology 

First-Line Therapy For Advanced Non–Clear Cell Renal Cell CarcinomaA Systematic Review and Meta-Analysis

 journal of Hepatology

Carvedilol vs. propranolol for the prevention of decompensation and mortality in patients with compensated and decompensated cirrhosis

 Gastroenterology

Mebeverine and the Influence of Labeling in Adolescents With Irritable Bowel Syndrome or Functional Abdominal Pain Not Otherwise Specified: A 2 × 2 Randomized, Placebo-Controlled Trial

 Clinical Gastroenterology

 Association Between the Inflammatory Potential of Diet and Constipation Among Adults in the United States: A Cross-sectional Study

  Circulation

Nonculprit Vulnerable Plaques and Prognosis in Myocardial Infarction With Versus Without ST-Segment Elevation: A PROSPECT II Substudy

 Journals of the American College of Cardiology

10-Year Outcome of Complete or Infarct Artery-Only Revascularization in STEMI With Multivessel Disease: The DANAMI-3-PRIMULTI Study

 JAMA Cardiology

Mode of Death in Patients With Heart Failure With Mildly Reduced or Preserved Ejection FractionThe FINEARTS-HF Randomized Clinical Trial

 Journal of Clinical Endocrinology & Metabolism

Tumor Volume Doubling Time of Less Than 1 Year Is Associated With a Higher Risk of Death From Medullary Thyroid Cancer

 Diabetes care

Associations of AMH in Midreproductive Years with Bone Mineral Density and Turnover Markers in Midlife

 Neurology

Risk of Ventricular Arrhythmia and Sudden Cardiac Arrest Among Older Patients Using Lamotrigine for Epilepsy

 Chest

Trajectories of Interferon-Gamma Release Assay Results Over 2 Years in Independent Cohorts From China, South Africa, Tanzania, and the United States

 The American Journal of Respiratory and Critical Care Medicine

Iloprost for the Treatment of Severe Septic Shock with Persistent Hypoperfusion: A Double-Blind, Randomized Controlled Trial

  Clinical Journal of American Society of Nephrology

Decision Readiness and Determinants of KRT among Veterans with Advanced CKD

  Kidney International reports

Low Energy Diets for Obesity and CKD (SLOW-CKD Randomized Feasibility Study)