813-人脑新皮层功能层级的全生命周期演变 episode artwork

EPISODE · Apr 18, 2026 · 28 MIN

813-人脑新皮层功能层级的全生命周期演变

from 聊聊Sci

这项研究通过分析从新生儿到百岁老人的大规模数据,构建了人类大脑皮层功能分级结构的终身演变图谱。研究发现,大脑连接通过感觉—关联(SA)、视觉—躯体运动(VS)和调制—表征(MR)三大主轴进行组织,这些轴线在婴儿期由初级感觉系统锚定,在青少年期向高级认知功能分化,并在老年期逐渐去分化。这些功能梯度的非线性轨迹与认知表现、皮层微结构以及基因表达特征高度相关。特别是SA轴的完整性被证实是衡量成年人智力与认知能力的关键指标。该研究不仅揭示了大脑发育与衰老的系统性规律,还为理解神经发育障碍和退行性疾病提供了重要的规范性参照。References: Taylor IV H P, Huynh K M, Thung K H, et al. Functional hierarchy of the human neocortex across the lifespan[J]. Nature, 2026: 1-10.前往小宇宙评论区与主播互动

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813-人脑新皮层功能层级的全生命周期演变

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