824: The Menopause Gut: Endogenous GLP-1, Akkermansia, and Hacking Midlife Insulin Resistance episode artwork

EPISODE · Apr 21, 2026 · 44 MIN

824: The Menopause Gut: Endogenous GLP-1, Akkermansia, and Hacking Midlife Insulin Resistance

from Beauty Bytes with Dr. Kay: Secrets of a Plastic Surgeon™

Why do so many women suddenly experience mysterious bloating, weight-loss resistance, and severe brain fog the moment they hit midlife? In this timely episode of Beauty Bytes, I am joined by Cynthia Thurlow, a nurse practitioner, host of the Everyday Wellness podcast, and author of the highly anticipated new book, The Menopause Gut . We dive deep into a conversation that the medical community has ignored for far too long: the critical connection between declining estrogen and your microbiome . Cynthia explains the concept of the "estrobolome" and reveals how the loss of estrogen literally breaks down the mortar of your intestinal walls, causing leaky gut, new food sensitivities, and systemic inflammation . We explore why treating midlife mood changes might actually start in the digestive tract, considering 70 to 80% of our neurotransmitters are produced in the gut. Cynthia also breaks down the harsh reality of midlife insulin resistance and sarcopenia, while giving us the exact blueprint for reversing it—from tracking macros to hit 100 grams of protein, to slowly building up to 25-30 grams of fiber to stimulate your body's natural GLP-1 production . We even tackle the taboo topic of why you must be pooping every single day to eliminate excess estrogen . If you are tired of being told that midlife weight gain and exhaustion are "just normal," this episode is your ultimate guide to taking your power back.Guest Information:Cynthia Thurlow is a nurse practitioner, international speaker, and host of the Everyday Wellness podcast. Her new book, The Menopause Gut, is available for pre-sale and officially launches on April 28. You can learn more and access her pre-sale bonuses at cynthiathurlow.com or follow her on Instagram

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824: The Menopause Gut: Endogenous GLP-1, Akkermansia, and Hacking Midlife Insulin Resistance

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