#85: Emily Mitchell - What You Need to Know About Decentralized Clinical Trials

What are decentralized clinical trials? What are the benefits of decentralized clinical trials? Why are decentralized clinical trials the way of the future?Emily Mitchell,  Executive Director of ICON’s DCT team, discusses the benefits of these trials and what needs to be considered to ensure these benefits are realized. Emily Mitchell has over 15 years of experience working in the CRO industry in Data Management, Project Management, and Clinical Operations. During her tenure at ICON, Emily partnered with an actigraphy vendor to run a pilot study with employees on the wear compliance and comparison of a medical grade activity tracker to a commercial grade version. Before the pandemic, Emily helped set up and support the first fully decentralized trial at ICON. She has continued to present at various conferences around the best practices for decentralized studies, ensuring minimized patient and site burden while optimizing data capture. Emily is an active member of the Society of Clinical Data Management (SCDM) and has presented about decentralized trials at numerous conferences.ICON is the only CRO to offer all services (without the need to contract third-party services or technology) and deliver end-to-end integrated decentralized clinical trial solutions.  ICON supported the delivery of the first decentralized clinical trial that has had positive published results in a medical journal – Nature MedicineWe are talking about⭐ Decentralized clinical trials⭐How they benefit patients⭐The impact on budgeting⭐Successful deployment of clinical trials an⭐ Much, much moreYoutube🕛 Timestamps:(00:00) Intro(03:30) Kick off with Summer Weather(06:30) What are Decentralized Clinical Trials (DCT)(07:30) Benefits of DCT(08:45) Real-Life Example for a DCT from ICON Plc(11:48) What was the Motivation to Develop the DCT Model before the Pandemic?(14:30) Logistics in Clinical Trials(16:20) Managing DCT(17:45) Patient Response to DCT(18:35) Benefits of DCT in Increasing Diversity in Patients Population(22:30) More Diversity in Patient Population Equals More Valuable Data(26:00) The Role of Social Media in Patient Recruitment(27:22) Data Management in Decentralized Clinical Trials(29:25) Improvement in Data Collection With AI/ML, Tablets, And Wearables(31:07) DCT and associated cost(34:08) Which Indications are suitable for DCT?(37:30) How do decentralized clinical trials impact the duration of a trial?(40:15) How long does the planning phase in a DCT model take?(43:30) ICON’s Partnership Model(47:13) The Demographics of Social Media as a Recruitment Tool for Clinical Trials(50:10) Patient Experience in DCT(52:57) How to Keep Patients Motivated Through a DCT(56:00) Data Collection by Patients(57:40) Long-term follow-ups in the DCT Model(01:00:55) Patient Empowerment in Decentralized Clinical Trials(01:02:45) Do You Want to Evaluate Decentralized Clinical Trials? Here are the next steps ([email protected])  Do you want to support the podcast? Join the LSG2G Community: https://lsg2g.substack.com/subscribeSend us Fan Mail Join Christian Soschner for expert coaching. 50% Off - With 35+ years in deep tech, startups/scaleups, and public companies, Christian offers power video sessions. Elevate strategy, execution, and leadership. Book Now.The LSG2G PartnersExperts in Life ScienceDisclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showJoin the Podcast Newsletter: Link