EPISODE · May 1, 2026 · 20 MIN
885-母亲攻击行为的神经环路与可塑性机制
from 聊聊Sci
这项研究揭示了哺乳期母鼠攻击行为波动的神经回路机制。研究重点关注从后杏仁核（PA）到下丘脑腹侧中心（VMHvl）的特定神经通路。实验证明，该回路在哺乳期间通过突触增强和神经元兴奋性提高发生显著的可塑性变化，从而使母鼠能迅速产生保护幼崽的攻击性。此外，催产素（Oxytocin）在调节这一回路中起到了核心作用，它能增强PA神经元的输出；而当幼崽不在身边导致催产素水平下降时，母鼠的攻击性也随之减弱。这些发现为理解激素变化与社会行为之间的自适应转换提供了关键的细胞学基础。References: Yamaguchi T, Yan R, Khan M, et al. The neural mechanisms supporting the rise and fall of maternal aggression[J]. Nature, 2026: 1-11.前往小宇宙评论区与主播互动
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