9 15 2025

Hi, This Week in Medicine, we will be discussing New England Journal of Medicine Aficamten or Metoprolol Monotherapy for Obstructive Hypertrophic Cardiomyopathy Mavacamten in Symptomatic Nonobstructive Hypertrophic Cardiomyopathy Multidomain Rehabilitation for Older Patients with Myocardial Infarction  Journal of  American Medical AssociationBiparametric vs Multiparametric MRI for Prostate Cancer DiagnosisThe PRIME Diagnostic Clinical Trial  Annals of Internal MedicineExposure to CT and Pregnancy Outcomes  British Medical JournalSecond cancers in 475 000 women with early invasive breast cancer diagnosed in England during 1993-2016  LancetBenefit–harm trade-offs of intensive blood pressure control versus standard blood pressure control on cardiovascular and renal outcomes: an individual participant data analysis of randomised controlled trialsJAMA oncology Debt, Bankruptcy, and Credit Scores After Cancer Diagnosis  Journal of Clinical Rheumatology Pilot Study: Development and Evaluation of Validity Evidence of a Low-Cost, Low-Fidelity Hand Model to Teach Clinical Assessment of Small Joint Swelling in Inflammatory Arthritis  Journals of the American College of CardiologyTrajectories of Angina After Initial Invasive vs Conservative Strategy for Chronic Coronary Disease JAMA CardiologyPolygenic Prediction of Peripheral Artery Disease and Major Adverse Limb Events  Journal of Clinical Endocrinology & MetabolismYAP1 Is a Prognostic Marker and Its Inhibition Reduces Tumor Progression in Adrenocortical Tumors Diabetes careGlucagon-Like Peptide 1 Receptor Agonists and the Risk of Emergency Department Visits and Hospitalization in Patients With Chronic Kidney Disease   NeurologyAssociation of Polygenic Susceptibility to Hyperlipidemia With Cholesterol Control and Recurrent Stroke in Ischemic Stroke Survivors   ChestAssociation of Timely Spirometry With Lower All-Cause Mortality  Risk Factors for Patient-Important Upper Gastrointestinal Bleeding Clinical Journal of American Society of NephrologyPregnancy and Long-Term Kidney Function in CKD: A Systematic Review and Meta-Analysis Kidney International reportsMeta-Analysis of Randomized Controlled Trials on Gamma-Aminobutyric Acid Analogues and Opioid-Based Therapies for CKD-Associated Pruritus A Systematic Review of Sleep Hygiene Strategy in CKD