EPISODE · May 12, 2026 · 17 MIN
951-脑深部刺激对帕金森患者功能网络的影响研究
from 聊聊Sci
这项研究利用3-T磁共振兼容技术，深入探讨了脑深部刺激（DBS）治疗帕金森病的神经机制。研究人员对14名患者进行了为期一年的精密神经影像随访，通过长达11.7小时的功能磁共振扫描，获取了极高可靠性的个体化大脑数据。结果表明，DBS能有效修复体感认知动作网络（SCAN）的连通性，且个体化的功能连接特征能精准预测临床治疗效果。通过对比不同频率的刺激方案，研究发现高频刺激在改善运动症状和恢复神经环路功能方面表现最优。该研究通过开放大规模纵向数据集，为实现帕金森病的个性化精准医疗提供了重要的科学依据。References:Ren J, Jiang C, Zhang W, et al. Circuit response to neuromodulation characterized with simultaneous deep brain stimulation and precision neuroimaging in humans[J]. Nature Neuroscience, 2026: 1-13.前往小宇宙评论区与主播互动
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951-脑深部刺激对帕金森患者功能网络的影响研究
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