A Journey through Academia, Big Pharma and Biotech: Building Breakthrough Medicines with Dr. Briggs Morrison

In this episode of Clinical Trialblazers, host Alberto Grignolo sits down with Dr. Briggs Morrison, CEO of Crossbow Therapeutics and former Chief Medical Officer and Head of Global Medicines Development at AstraZeneca. Briggs shares lessons from a career spanning academia, Big Pharma, and biotech entrepreneurship—including leadership roles at Merck, Pfizer, AstraZeneca, Syndax Pharmaceuticals, and now Crossbow. The conversation explores how small biotech companies drive innovation, why constraints can improve execution, and how leaders build teams capable of navigating scientific, clinical, and financial uncertainty. Briggs also discusses Crossbow's recent $77 million Series B financing, the promise of TCR mimetic antibody therapies, and the realities of raising capital in today's biotech environment. We hope you enjoyed this week’s episode of Clinical Trialblazers. Please take a moment to rate and review this podcast wherever you listen. Special thanks to our production partner, Wonder Media Network. Our producer is Brittany Martinez, our editor is Gianna Palmer and our production assistant is Joia Putnoi.