A new ARPA‑H effort aims to change how doctors understand and treat critical illness in real time

from The Federal Drive with Terry Gerton

When patients become critically ill, their bodies often fall into a dangerous immune response loop that today’s ICU tools can’t fully see or stop. The CIRCLE program aims to give doctors a clearer roadmap by combining new sensors, faster lab insights, and digital models that predict how a patient will respond. Joining me to discuss long‑term promise for ICU care is Dr. Yoram Vodovotz, Program Manager for CIRCLE at ARPA‑H.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What this episode covers

When patients become critically ill, their bodies often fall into a dangerous immune response loop that today’s ICU tools can’t fully see or stop. The CIRCLE program aims to give doctors a clearer roadmap by combining new sensors, faster lab insights, and digital models that predict how a patient will respond. Joining me to discuss long‑term promise for ICU care is Dr. Yoram Vodovotz, Program Manager for CIRCLE at ARPA‑H. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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A new ARPA‑H effort aims to change how doctors understand and treat critical illness in real time

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This episode is 10 minutes long.

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This episode was published on April 3, 2026.

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