A new ARPA‑H effort aims to change how doctors understand and treat critical illness in real time

When patients become critically ill, their bodies often fall into a dangerous immune response loop that today’s ICU tools can’t fully see or stop. The CIRCLE program aims to give doctors a clearer roadmap by combining new sensors, faster lab insights, and digital models that predict how a patient will respond. Joining me to discuss long‑term promise for ICU care is Dr. Yoram Vodovotz, Program Manager for CIRCLE at ARPA‑H.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.